Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 10/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 10/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 6/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11991240 | 0.91 | ESR1 (0.51) | ESR1ESR2MEN1KMT2AJAK2 | |
| SCHEMBL18785662 | 0.84 | ELANE (0.53) | ESR1ESR2MEN1KMT2AJAK2 | |
| SCHEMBL22454743 | 0.81 | ESR1 (0.46) | ESR1ESR2MEN1KMT2AJAK2 | |
| SCHEMBL11991243 | 0.80 | ALDH1A1 (0.54) | MEN1KMT2AGAAHSD17B10ELANE | |
| SCHEMBL15189295 | 0.79 | ESR1 (0.49) | ESR1ESR2MEN1KMT2AJAK2 | |
| SCHEMBL8737835 | 0.79 | ESR1 (0.44) | ESR1ESR2MEN1KMT2AJAK2 | |
| SCHEMBL18671905 | 0.77 | ESR1 (0.42) | ESR1ESR2MEN1KMT2AJAK2 | |
| Methylsulfanylmethane SCHEMBL5636396 | 0.76 | ESR1 (0.44) | ESR1ESR2MEN1KMT2AJAK2 | |
| SCHEMBL13161550 | 0.75 | ESR1 (0.41) | ESR1ESR2MEN1KMT2AJAK2 | |
| SCHEMBL27842430 | 0.75 | ESR1 (0.53) | ESR1ESR2MEN1KMT2AJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120214100-A1 | RESIST COMPOSITION AND PATTERNING PROCESS USING THE SAME | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2012-08-23 | — | — | US | disclosed |