Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TOP1 | P11387 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2253326 | 0.96 | LMNA (0.48) | LMNAL3MBTL1USP2SLCO1B1TDP1 | |
| Hydrochloric Acid SCHEMBL18115133 | 0.96 | LMNA (0.48) | LMNAL3MBTL1USP2SLCO1B1TDP1 | |
| Hydrochloric Acid SCHEMBL4112448 | 0.96 | LMNA (0.48) | LMNAL3MBTL1USP2SLCO1B1TDP1 | |
| SCHEMBL5706423 | 0.96 | LMNA (0.52) | LMNAL3MBTL1USP2SLCO1B1TDP1 | |
| SCHEMBL19426406 | 0.96 | LMNA (0.52) | LMNAL3MBTL1USP2SLCO1B1TDP1 | |
| SCHEMBL5706429 | 0.96 | LMNA (0.52) | LMNAL3MBTL1USP2SLCO1B1TDP1 | |
| SCHEMBL2560773 | 0.96 | LMNA (0.52) | LMNAL3MBTL1USP2SLCO1B1TDP1 | |
| SCHEMBL22963142 | 0.96 | LMNA (0.52) | LMNAL3MBTL1USP2SLCO1B1TDP1 | |
| SCHEMBL28730 | 0.96 | LMNA (0.52) | LMNAL3MBTL1USP2SLCO1B1TDP1 | |
| SCHEMBL1548302 | 0.96 | LMNA (0.52) | LMNAL3MBTL1USP2SLCO1B1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-218269879-U | A drying device that is used for glucosamine sulfate sodium chloride double salt to prepare | 深圳市罗素医药有限公司 | 2023-01-10 | — | — | CN | disclosed |
| US-20110027357-A1 | Compositions and methods for timed release of water-soluble nutritional supplements | OSMOPHARM USA, LLC | 2011-02-03 | — | — | US | disclosed |
| WO-2005079764-A1 | COMPOSITIONS AND METHODS FOR TIMED RELEASE OF WATER-SOLUBLE NUTRITIONAL SUPPLEMENTS | OSMOPHARM USA (US) | 2005-09-01 | — | — | WO | disclosed |
| US-20050181048-A1 | Compositions and methods for timed release of a water-soluble nutritional supplement, methylsulfonylmethane | ROMERO JAIME (CO) | 2005-08-18 | — | — | US | disclosed |
| US-20050181044-A1 | Compositions and methods for timed release of water-soluble nutritional supplements, green coffee extract | ROMERO JAIME (CO) | 2005-08-18 | — | — | US | disclosed |
| US-20050181047-A1 | Compositions and methods for timed release of water-soluble nutritional supplements | OSMOPHARM USA LLC | 2005-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050181048-A1 | Compositions and methods for timed release of a water-soluble nutritional supplement, methylsulfonylmethane | BHMT2, CCNE2, CCNH | LMNA 2162/4885L3MBTL1 2335/4885USP2 147/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.