Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | SELPLG | Q14242 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5551237 | 0.85 | TSHR (0.55) | TSHRCA12CA1CA2CA9 | |
| Ethane SCHEMBL5663955 | 0.83 | TSHR (0.53) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL28114560 | 0.82 | TSHR (0.58) | TSHRSELPLGCA12CA1CA2 | |
| SCHEMBL11996560 | 0.82 | TSHR (0.48) | TSHRPTGS2CA12CA1CA2 | |
| SCHEMBL9908237 | 0.81 | CA12 (0.56) | TSHRPTGS2CA12CA1CA2 | |
| SCHEMBL8731749 | 0.80 | TSHR (0.64) | TSHRCYP1A2MEN1KMT2AHPGD | |
| SCHEMBL11996556 | 0.79 | ABCB1 (0.50) | TSHRMEN1KMT2AABCB1NPSR1 | |
| SCHEMBL11996568 | 0.79 | TSHR (0.46) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL22193249 | 0.79 | TSHR (0.46) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL25872426 | 0.79 | TSHR (0.46) | TSHRSELPLGC3AR1SLC6A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120214798-A1 | Novel Ethanediamone Hepcidine Antagonists | VIFOR (INTERNATIONAL) AG (CH) | 2012-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120214798-A1 | Novel Ethanediamone Hepcidine Antagonists | HAMP, SLC40A1, FTH1 | TSHR 1790/4885SELPLG 905/4885PTGS2 252/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.