SCHEMBL11997129

SCHEMBL11997129

Cc1ccc(NS(=O)(=O)c2cccnc2)c2ncccc12

nearest known ligand 0.79

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC40A1 Q9NP59 11/20 0.79
CKS1B P61024 7/20 0.70
SKP2 Q13309 7/20 0.70
GLO1 Q04760 1/20 0.64
MEN1 O00255 2/20 0.61
KMT2A Q03164 2/20 0.61
TDP1 Q9NUW8 2/20 0.61
PKM P14618 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11972688 0.88 SLC40A1 (1.00) SLC40A1CKS1BSKP2GLO1MEN1
SCHEMBL11995650 0.85 SLC40A1 (1.00) SLC40A1CKS1BSKP2GLO1MEN1
SCHEMBL17506517 0.82 CKS1B (1.00) SLC40A1CKS1BSKP2GLO1
SCHEMBL17506530 0.81 CKS1B (1.00) SLC40A1CKS1BSKP2GLO1
SCHEMBL17506543 0.81 CKS1B (1.00) SLC40A1CKS1BSKP2GLO1
SCHEMBL17570174 0.79 SLC40A1 (0.70) SLC40A1CKS1BSKP2GLO1MEN1
SCHEMBL27214254 0.79 SLC40A1 (0.74) SLC40A1GLO1MEN1KMT2ATDP1
SCHEMBL30925462 0.79 SLC40A1 (1.00) SLC40A1CKS1BSKP2GLO1MEN1
SCHEMBL11973652 0.79 SLC40A1 (1.00) SLC40A1CKS1BSKP2GLO1MEN1
SCHEMBL30925439 0.79 SLC40A1 (0.70) SLC40A1CKS1BSKP2GLO1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120214803-A1 Novel Sulfonaminoquinoline Hepcidin Antagonists VIFOR (INTERNATIONAL) AG (CH) 2012-08-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120214803-A1 Novel Sulfonaminoquinoline Hepcidin Antagonists HAMP, SLC40A1, FTH1 SLC40A1 2/4885CKS1B 3744/4885SKP2 346/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.