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Sugi Predict / Compounds / SCHEMBL11997511

SCHEMBL11997511

SCHEMBL11997511

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nearest known ligand 0.35

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ LGALS3 P17931 2/20 0.35
▸ LGALS8 O00214 1/20 0.35
▸ LGALS4 P56470 1/20 0.35
▸ BDNF P23560 3/20 0.34
▸ PTN P21246 2/20 0.34
▸ MDK P21741 2/20 0.34
▸ SIGLEC7 Q9Y286 1/20 0.33
▸ MCHR1 Q99705 2/20 0.32
▸ SLC6A2 P23975 1/20 0.32
▸ SSTR2 P30874 2/20 0.32
▸ SSTR3 P32745 2/20 0.32
▸ SSTR5 P35346 2/20 0.32
▸ VEGFA P15692 2/20 0.32
▸ BMP2 P12643 1/20 0.32
▸ CXCL12 P48061 1/20 0.32
▸ SHH Q15465 1/20 0.32
▸ B4GALT1 P15291 1/20 0.32
▸ FGF1 P05230 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11997506 0.93 LGALS3 (0.35) LGALS3LGALS8LGALS4BDNFPTN
SCHEMBL11997498 0.90 BDNF (0.42) LGALS3LGALS8LGALS4BDNFPTN
SCHEMBL11997510 0.83 CA1 (0.33) LGALS3LGALS8LGALS4BDNFPTN
SCHEMBL11997494 0.80 VEGFA (0.43) LGALS3LGALS8LGALS4BDNFPTN
SCHEMBL11997495 0.80 VEGFA (0.43) LGALS3LGALS8LGALS4BDNFPTN
SCHEMBL11997497 0.79 VEGFA (0.49) LGALS3LGALS8LGALS4BDNFPTN
SCHEMBL11997493 0.78 VEGFA (0.50) LGALS3LGALS8LGALS4BDNFPTN
SCHEMBL11997502 0.76 CD69 (0.40) LGALS3LGALS8LGALS4BDNFPTN
SCHEMBL11997503 0.76 CD69 (0.40) LGALS3LGALS8LGALS4BDNFPTN
SCHEMBL11997501 0.76 CD69 (0.40) LGALS3LGALS8LGALS4BDNFPTN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9012413-B2 FGF receptor-activating N-acyl octasaccharides, preparation thereof, and therapeutic use thereof SANOFI (FR) 2015-04-21 — — US disclosed
US-20120214754-A1 FGF RECEPTOR-ACTIVATING N-ACYL OCTASACCHARIDES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF SANOFI (FR) 2012-08-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120214754-A1 FGF RECEPTOR-ACTIVATING N-ACYL OCTASACCHARIDES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF FGFR1, FGF2, FGFR3 LGALS3 698/4885LGALS8 562/4885LGALS4 860/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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