Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.43 |
| ▸ | KCNA2 | P16389 | 1/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.42 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.39 |
| ▸ | EDNRA | P25101 | 1/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1590791 | 0.84 | ALDH1A1 (0.52) | ALDH1A1USP2TSHRHSD17B10KCNA2 | |
| SCHEMBL1974562 | 0.83 | DHODH (0.44) | ALDH1A1TSHRHSD17B10KDM4ELMNA | |
| SCHEMBL14431116 | 0.83 | ALDH1A1 (0.44) | ALDH1A1USP2TSHRHSD17B10KCNA2 | |
| SCHEMBL9606562 | 0.82 | KMT2A (0.38) | ALDH1A1TSHRHSD17B10KDM4ELMNA | |
| SCHEMBL1590125 | 0.82 | EDNRA (0.52) | ALDH1A1USP2TSHRHSD17B10GLRA1 | |
| SCHEMBL13177151 | 0.82 | LTB4R (0.45) | ALDH1A1USP2TSHRHSD17B10KCNA2 | |
| SCHEMBL1590143 | 0.80 | ALDH1A1 (0.49) | ALDH1A1USP2TSHRHSD17B10GLRA1 | |
| SCHEMBL1591366 | 0.80 | KCNA3 (0.55) | ALDH1A1USP2TSHRHSD17B10KCNA2 | |
| SCHEMBL12002194 | 0.78 | ALDH1A1 (0.43) | ALDH1A1USP2TSHRHSD17B10GLRA1 | |
| SCHEMBL1590385 | 0.78 | ALDH1A1 (0.47) | ALDH1A1USP2TSHRHSD17B10GLRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979317-B1 | BENZOISOINDOLE DERIVATIVES FOR THE TREATMENT OF PAIN | GLAXO GROUP LTD (GB) | 2012-08-22 | — | — | EP | disclosed |
| WO-2007088189-A1 | BENZOISOINDOLE DERIVATIVES FOR THE TREATMENT OF PAIN | GLAXO GROUP LIMITED (GB) | 2007-08-09 | — | — | WO | disclosed |