Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.72 |
| ▸ | CA2 | P00918 | 4/20 | 0.72 |
| ▸ | GAA | P10253 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | MME | P08473 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.52 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.52 |
| ▸ | ACE | P12821 | 2/20 | 0.52 |
| ▸ | FPR2 | P25090 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12002473 | 1.00 | CA1 (0.72) | CA1CA2GAAKMT2AMME | |
| SCHEMBL12002557 | 0.91 | CA1 (0.74) | CA1CA2GAAKMT2AMME | |
| SCHEMBL12002558 | 0.91 | CA1 (0.74) | CA1CA2GAAKMT2AMME | |
| SCHEMBL20335037 | 0.87 | ALDH1A1 (0.59) | CA1CA2GAAKMT2ALMNA | |
| SCHEMBL20335039 | 0.87 | ALDH1A1 (0.59) | CA1CA2GAAKMT2ALMNA | |
| SCHEMBL24064907 | 0.86 | CA1 (0.62) | CA1CA2GAAMMEFOLH1 | |
| SCHEMBL6021262 | 0.83 | CTSL (0.68) | CA1CA2 | |
| SCHEMBL20335071 | 0.82 | CA1 (0.70) | CA1CA2GAAKMT2AFPR2 | |
| SCHEMBL20335070 | 0.82 | CA1 (0.70) | CA1CA2GAAKMT2AFPR2 | |
| SCHEMBL6019837 | 0.80 | CTSL (0.55) | CA1CA2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140297195-A1 | Method and Use of Metabolites for the Diagnosis of Inflammatory Brain Injury in Preterm Born Infants | INFANDX AG (DE) | 2014-10-02 | — | — | US | claimed |
| WO-2012113834-A1 | METHOD AND USE OF METABOLITES FOR THE DIAGNOSIS OF INFLAMMATORY BRAIN INJURY IN PRETERM BORN INFANTS | BIOCRATES LIFE SCIENCES AG (AT) | 2012-08-30 | — | — | WO | claimed |
| EP-2492690-A1 | Method and use of metabolites for the diagnosis of inflammatory brain injury in preterm born infants | BIOCRATES Life Sciences AG (AT) | 2012-08-29 | — | — | EP | claimed |
| US-20210372959-A1 | Nanopore Method for Identifying Single Amino Acid in Oligopeptides | UNIVERSITY OF SOUTH CAROLINA (US) | 2021-12-02 | — | — | US | disclosed |
| EP-2678690-B1 | METHOD AND USE OF METABOLITES FOR THE DIAGNOSIS OF INFLAMMATORY BRAIN INJURY IN PRETERM BORN INFANTS | INFANDX AG (DE) | 2018-01-24 | — | — | EP | disclosed |
| US-20140297195-A1 | Method and Use of Metabolites for the Diagnosis of Inflammatory Brain Injury in Preterm Born Infants | INFANDX AG (DE) | 2014-10-02 | — | — | US | disclosed |
| WO-2012113834-A1 | METHOD AND USE OF METABOLITES FOR THE DIAGNOSIS OF INFLAMMATORY BRAIN INJURY IN PRETERM BORN INFANTS | BIOCRATES LIFE SCIENCES AG (AT) | 2012-08-30 | — | — | WO | disclosed |
| EP-2492690-A1 | Method and use of metabolites for the diagnosis of inflammatory brain injury in preterm born infants | BIOCRATES Life Sciences AG (AT) | 2012-08-29 | — | — | EP | disclosed |