SCHEMBL20335071

SCHEMBL20335071

Cc1ccc(NC(=S)N[C@@H](Cc2ccccc2)C(=O)O)cc1

nearest known ligand 0.70

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ CA1 P00915 4/20 0.70
▸ CA2 P00918 4/20 0.70
▸ FPR2 P25090 8/20 0.56
▸ GAA P10253 2/20 0.56
▸ MMP9 P14780 1/20 0.55
▸ KMT2A Q03164 2/20 0.53
▸ ALDH1A1 P00352 2/20 0.52
▸ MEN1 O00255 1/20 0.52
▸ ALOX12 P18054 1/20 0.52
▸ L3MBTL1 Q9Y468 1/20 0.52
▸ NPC1 O15118 1/20 0.51
▸ MAPT P10636 1/20 0.51
▸ RAB9A P51151 1/20 0.51
▸ CCR6 P51684 1/20 0.51
▸ SMN1; SMN2 Q16637 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20335070 1.00 CA1 (0.70) CA1CA2FPR2GAAMMP9
SCHEMBL12002558 0.90 CA1 (0.74) CA1CA2FPR2GAAKMT2A
SCHEMBL12002557 0.90 CA1 (0.74) CA1CA2FPR2GAAKMT2A
SCHEMBL20335111 0.90 CA1 (0.60) CA1CA2GAAMMP9KMT2A
SCHEMBL20335113 0.90 CA1 (0.60) CA1CA2GAAMMP9KMT2A
SCHEMBL20334997 0.86 TACR1 (0.60) CA1CA2GAAKMT2AALDH1A1
SCHEMBL20334996 0.86 TACR1 (0.60) CA1CA2GAAKMT2AALDH1A1
SCHEMBL6376318 0.86 FPR2 (0.75) CA1CA2FPR2MMP9KMT2A
SCHEMBL6376315 0.86 FPR2 (0.75) CA1CA2FPR2MMP9KMT2A
SCHEMBL6379448 0.86 FPR2 (0.75) CA1CA2FPR2MMP9KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240399776-A1 COLOR DEVELOPER, THERMAL RECORDING MATERIAL, AND THERMAL RECORDING LAYER COATING MATERIAL SANKO CO., LTD. (JP) 2024-12-05 — — US disclosed
EP-4269119-A1 COLOR DEVELOPER, HEAT-SENSITIVE RECORDING MATERIAL, AND COATING MATERIAL FOR HEAT-SENSITIVE RECORDING LAYERS Sanko Co., Ltd. (JP) 2023-11-01 — — EP disclosed
EP-3342599-B1 HEAT-SENSITIVE RECORDING MATERIAL SANKO CO LTD (JP) 2021-06-16 — — EP disclosed
US-10086634-B2 Heat-sensitive recording material SANKO CO., LTD. (JP) 2018-10-02 — — US disclosed
US-20180194151-A1 HEAT-SENSITIVE RECORDING MATERIAL SANKO CO., LTD. (JP) 2018-07-12 — — US disclosed
EP-3342599-A1 HEAT-SENSITIVE RECORDING MATERIAL Sanko Co., Ltd. (JP) 2018-07-04 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180194151-A1 HEAT-SENSITIVE RECORDING MATERIAL ASIC1, SCN1A, NPR1 CA1 6/4885CA2 116/4885FPR2 622/4885
US-10086634-B2 Heat-sensitive recording material ASIC1, SCN1A, NPR1 CA1 8/4885CA2 89/4885FPR2 565/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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