Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 8/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | HSD17B1 | P14061 | 4/20 | 0.57 |
| ▸ | HSD17B2 | P37059 | 4/20 | 0.57 |
| ▸ | ABL1 | P00519 | 2/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.53 |
| ▸ | BCR | P11274 | 2/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | MMP3 | P08254 | 2/20 | 0.48 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12922964 | 0.92 | ESR1 (0.74) | ESR1MEN1KMT2AHSD17B1HSD17B2 | |
| SCHEMBL12922924 | 0.88 | ESR1 (0.68) | ESR1MEN1KMT2AHSD17B1HSD17B2 | |
| SCHEMBL1758100 | 0.85 | ESR1 (0.47) | ESR1MEN1KMT2AHSD17B1HSD17B2 | |
| SCHEMBL18637069 | 0.85 | ESR1 (0.48) | ESR1MEN1KMT2AHSD17B1HSD17B2 | |
| SCHEMBL18381150 | 0.85 | ESR1 (0.48) | ESR1MEN1KMT2AHSD17B1HSD17B2 | |
| SCHEMBL18642918 | 0.84 | ESR1 (0.47) | ESR1MEN1KMT2AHSD17B1HSD17B2 | |
| SCHEMBL3045847 | 0.83 | MMP3 (0.64) | ESR1MEN1KMT2AHSD17B1HSD17B2 | |
| SCHEMBL22238270 | 0.83 | MMP3 (0.64) | ESR1MEN1KMT2AHSD17B1HSD17B2 | |
| SCHEMBL12922919 | 0.83 | MMP3 (0.71) | ESR1MEN1KMT2AHSD17B1HSD17B2 | |
| SCHEMBL2862193 | 0.83 | MMP3 (0.71) | ESR1MEN1KMT2AHSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8816135-B2 | Trisphenol compound | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2014-08-26 | — | — | US | disclosed |
| US-20120220805-A1 | NOVEL TRISPHENOL COMPUND | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2012-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120220805-A1 | NOVEL TRISPHENOL COMPUND | NCOR1, NCOR2, NCOA1 | ESR1 40/4885MEN1 4005/4885KMT2A 2710/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.