Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 3/20 | 0.44 |
| ▸ | CCR1 | P32246 | 2/20 | 0.41 |
| ▸ | CCR8 | P51685 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12005378 | 0.83 | LMNA (0.47) | CYP2A6CCR1CCR8CYP3A4L3MBTL1 | |
| SCHEMBL17014652 | 0.80 | CYP2A6 (0.50) | CYP2A6KMT2AMEN1NPC1RAB9A | |
| SCHEMBL12006024 | 0.79 | CYP3A4 (0.42) | CYP2A6CCR1CCR8CYP3A4L3MBTL1 | |
| SCHEMBL12914230 | 0.76 | KDM4E (0.45) | CYP2A6CCR1CCR8CYP3A4L3MBTL1 | |
| SCHEMBL29985883 | 0.76 | CYP2A6 (0.53) | CYP2A6KMT2AMEN1NPC1RAB9A | |
| SCHEMBL21159958 | 0.76 | MAPT (0.44) | CYP3A4L3MBTL1KMT2AMEN1KDM4E | |
| SCHEMBL12006262 | 0.75 | CYP1A2 (0.36) | CYP2A6KDM4ENPSR1ALDH1A1CYP1A2 | |
| SCHEMBL31419878 | 0.75 | CYP2A6 (0.66) | CYP2A6KMT2AMEN1KDM4ERAB9A | |
| SCHEMBL29986300 | 0.75 | CYP2A6 (0.66) | CYP2A6KMT2AMEN1KDM4ERAB9A | |
| SCHEMBL17589450 | 0.75 | CYP2A6 (0.50) | CYP2A6CCR1CCR8L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8822696-B2 | Ligand for asymmetric synthesis catalyst, and process for production of alpha-alkenyl cyclic compound using the same | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2014-09-02 | — | — | US | disclosed |
| US-20120220780-A1 | LIGAND FOR ASYMMETRIC SYNTHESIS CATALYST, AND PROCESS FOR PRODUCTION OF ALPHA-ALKENYL CYCLIC COMPOUND USING SAME | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2012-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120220780-A1 | LIGAND FOR ASYMMETRIC SYNTHESIS CATALYST, AND PROCESS FOR PRODUCTION OF ALPHA-ALKENYL CYCLIC COMPOUND USING SAME | OR10J3, COASY, ACKR3 | CYP2A6 1580/4885CCR1 65/4885CCR8 239/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.