SCHEMBL17014652

SCHEMBL17014652

Cc1cccnc1-c1c(C)cccc1-c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.50
PTGS1 P23219 1/20 0.45
PTGS2 P35354 1/20 0.45
ALDH1A1 P00352 2/20 0.42
HTT P42858 1/20 0.42
HSD17B10 Q99714 1/20 0.42
NOS3 P29474 1/20 0.41
NOS1 P29475 1/20 0.41
NOS2 P35228 1/20 0.41
PDK2 Q15119 1/20 0.41
DPP4 P27487 1/20 0.39
KDR P35968 1/20 0.39
METAP2 P50579 1/20 0.39
MYC P01106 1/20 0.39
ADORA2A P29274 1/20 0.38
CTSL P07711 1/20 0.38
PTPRC P08575 1/20 0.38
CTSS P25774 1/20 0.38
PTPN13 Q12923 1/20 0.38
SQOR Q9Y6N5 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1133419 0.84 PTGS1 (0.50) CYP2A6PTGS1PTGS2ALDH1A1HTT
SCHEMBL10100787 0.84 CYP2A6 (0.55) CYP2A6PTGS1PTGS2ALDH1A1HTT
SCHEMBL29985883 0.82 CYP2A6 (0.53) CYP2A6PTGS1PTGS2ALDH1A1HTT
SCHEMBL12320089 0.81 NOS3 (0.54) CYP2A6NOS3NOS1NOS2PDK2
SCHEMBL12914249 0.81 CYP2A6 (0.51) CYP2A6PTGS1PTGS2ALDH1A1HTT
SCHEMBL12914226 0.81 GRM5 (0.47) CYP2A6HTTKDRNPC1TSHR
SCHEMBL30021754 0.80 PTGS2 (0.53) CYP2A6PTGS1PTGS2ALDH1A1HTT
SCHEMBL12005138 0.80 CYP2A6 (0.44) CYP2A6PTGS1PTGS2ALDH1A1HSD17B10
SCHEMBL64623 0.79 CYP2A6 (0.68) CYP2A6PTGS1PTGS2ALDH1A1NOS3
SCHEMBL32509667 0.79 CYP2A6 (0.68) CYP2A6PTGS1PTGS2ALDH1A1NOS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9847497-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2017-12-19 US disclosed
US-20150236279-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-08-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150236279-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES MLX, ZYX, LOXL1 CYP2A6 2680/4885PTGS1 3916/4885PTGS2 3906/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.