SCHEMBL12005276

SCHEMBL12005276

CCO[Si](CCCOC1(O)C=CC=CC1C(=O)c1ccccc1)(OCC)OCC

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.32
LMNA P02545 1/20 0.32
HTT P42858 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
NPC1 O15118 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4635207 0.83 LMNA (0.41) KDM4ELMNAHTTNPSR1NPC1
SCHEMBL7386572 0.83 NPC1 (0.37) LMNANPC1L3MBTL1
SCHEMBL9403246 0.79 GAA (0.36) HTTNPC1L3MBTL1
SCHEMBL820868 0.74 NPC1 (0.37) NPC1L3MBTL1
SCHEMBL2805922 0.74 NPC1 (0.40) HTTNPC1L3MBTL1
SCHEMBL17394347 0.72 CYP3A4 (0.34) KDM4ELMNANPC1L3MBTL1
SCHEMBL14813391 0.71 NPC1 (0.38) LMNAHTTNPC1L3MBTL1
SCHEMBL28359455 0.70 NPC1 (0.37) LMNANPC1L3MBTL1
SCHEMBL17891288 0.70 ELANE (0.42) NPC1L3MBTL1
SCHEMBL1224989 0.69 TDP1 (0.62) LMNANPC1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8940397-B2 Weatherable and abrasion resistant coating systems for polymeric substrates MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2015-01-27 US disclosed
US-20120219803-A1 Weatherable & Abrasion Resistant Coating Systems for Polymeric Substrates MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-08-30 US disclosed