Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7386572 | 0.84 | NPC1 (0.37) | NPC1L3MBTL1ALDH1A1MAPTTSHR | |
| SCHEMBL4635207 | 0.82 | LMNA (0.41) | NPC1L3MBTL1ALDH1A1MAPTTSHR | |
| SCHEMBL17394347 | 0.81 | CYP3A4 (0.34) | NPC1L3MBTL1ALDH1A1MAPTTSHR | |
| SCHEMBL17891288 | 0.81 | ELANE (0.42) | NPC1L3MBTL1ALDH1A1MAPTMMP9 | |
| SCHEMBL9403246 | 0.81 | GAA (0.36) | NPC1L3MBTL1ALDH1A1MAPTTSHR | |
| SCHEMBL5150393 | 0.81 | KMT2A (0.40) | NPC1L3MBTL1ALDH1A1MAPTTSHR | |
| SCHEMBL2805922 | 0.80 | NPC1 (0.40) | NPC1L3MBTL1ALDH1A1MAPTTSHR | |
| SCHEMBL5137770 | 0.78 | CES2 (0.41) | ALDH1A1TSHRCYP3A4 | |
| SCHEMBL12005276 | 0.74 | KDM4E (0.32) | NPC1L3MBTL1 | |
| SCHEMBL22572616 | 0.72 | NPC1 (0.38) | NPC1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10829710-B2 | Slipperiness-imparting agent and slipperiness-imparting method | NOF CORPORATION (JP) | 2020-11-10 | — | — | US | claimed |
| US-20080031918-A1 | BARRIERS FOR POLYMERIC COATINGS | SURMODICS, INC. | 2008-02-07 | — | — | US | claimed |
| EP-1567203-B1 | BARRIERS FOR BIOACTIVE AGENT-CONTAINING POLYMERIC COATINGS | SURMODICS INC (US) | 2007-09-26 | — | — | EP | claimed |
| JP-3954616-B2 | — | — | 2007-08-08 | — | — | JP | claimed |
| US-7097850-B2 | Bioactive agent release coating and controlled humidity method | SURMODICS, INC. (US) | 2006-08-29 | — | — | US | claimed |
| EP-1551469-B1 | BIOACTIVE AGENT RELEASE COATING WITH AROMATIC POLY(METH)ACRYLATES | SURMODICS INC (US) | 2006-03-08 | — | — | EP | claimed |
| JP-2006505303-A | — | — | 2006-02-16 | — | — | JP | claimed |
| EP-1567203-A2 | BARRIERS FOR BIOACTIVE AGENT-CONTAINING POLYMERIC COATINGS | SurModics, Inc. (US) | 2005-08-31 | — | — | EP | claimed |
| EP-1551469-A1 | BIOACTIVE AGENT RELEASE COATING WITH AROMATIC POLY(METH)ACRYLATES | SurModics, Inc. (US) | 2005-07-13 | — | — | EP | claimed |
| EP-1534354-A1 | METHOD AND SYSTEM FOR PROVIDING BIOACTIVE AGENT RELEASE COATING | SurModics, Inc. (US) | 2005-06-01 | — | — | EP | claimed |
| EP-1517714-A1 | BIOACTIVE AGENT RELEASE COATING AND CONTROLLED HUMIDITY METHOD | SurModics, Inc. (US) | 2005-03-30 | — | — | EP | claimed |
| WO-2004052420-A2 | BARRIERS FOR BIOACTIVE AGENT-CONTAINING POLYMERIC COATINGS | SURMODICS, INC. (US) | 2004-06-24 | — | — | WO | claimed |
| US-20040111144-A1 | Barriers for polymeric coatings | Surmodics Coatings, LLC | 2004-06-10 | — | — | US | claimed |
| WO-2003105920-A1 | METHOD AND SYSTEM FOR PROVIDING BIOACTIVE AGENT RELEASE COATING | SURMODICS, INC. (US) | 2003-12-24 | — | — | WO | claimed |
| WO-2003105919-A1 | BIOACTIVE AGENT RELEASE COATING AND CONTROLLED HUMIDITY METHOD | SURMODICS, INC. (US) | 2003-12-24 | — | — | WO | claimed |
| WO-2003105918-A1 | BIOACTIVE AGENT RELEASE COATING WITH AROMATIC POLY(METH)ACRYLATES | SURMODICS, INC. (US) | 2003-12-24 | — | — | WO | claimed |
| US-20030232087-A1 | Bioactive agent release coating with aromatic poly(meth)acrylates | Surmodics Coatings, LLC | 2003-12-18 | — | — | US | claimed |
| US-20030232122-A1 | Bioactive agent release coating and controlled humidity method | Surmodics Coatings, LLC | 2003-12-18 | — | — | US | claimed |
| US-20020188037-A1 | Method and system for providing bioactive agent release coating | Surmodics Coatings, LLC | 2002-12-12 | — | — | US | claimed |
| EP-3728339-A1 | COMPOSITION FOR OPHTHALMOLOGICAL PRODUCTS | Merck Patent GmbH (DE) | 2020-10-28 | — | — | EP | disclosed |
| EP-3697443-A1 | METHODS FOR ENHANCING 5-AMINOLEVULINIC ACID-BASED MEDICAL IMAGING AND PHOTOTHERAPY | Nanoco Technologies Ltd (GB) | 2020-08-26 | — | — | EP | disclosed |
| WO-2019077362-A1 | METHODS FOR ENHANCING 5-AMINOLEVULINIC ACID-BASED MEDICAL IMAGING AND PHOTOTHERAPY | NANOCO TECHNOLOGIES LTD (GB) | 2019-04-25 | — | — | WO | disclosed |
| EP-2890760-A2 | DUAL MECHANISM THICKENING AGENTS FOR HYDRAULIC FRACTURING FLUIDS | ATRP Solutions, Inc. (US) | 2015-07-08 | — | — | EP | disclosed |
| WO-2014036498-A2 | DUAL MECHANISM THICKENING AGENTS FOR HYDRAULIC FRACTURING FLUIDS | ATRP Solutions, Inc. (US) | 2014-03-06 | — | — | WO | disclosed |
| US-8246974-B2 | Longitudinal body; polymeric coating of polyalkyl(meth)acrylate and/or aromatic poly(meth)acrylate; and poly(ethylene-co-vinyl acetate); triamcinolone acetonide; drug delivery to eye | SURMODICS, INC. (US) | 2012-08-21 | — | — | US | disclosed |
| US-20120165760-A1 | DRUG ELUTING IMPLANT | SURMODICS, INC. (US) | 2012-06-28 | — | — | US | disclosed |
| US-20120010707-A1 | METHODS AND REAGENTS FOR PREPARING BIOMOLECULE-CONTAINING COATINGS | Surmodics Coatings, LLC | 2012-01-12 | — | — | US | disclosed |
| US-8034369-B2 | Longitudinal body with polymeric coating; triamcinolone acetonide; drug delivery to eye | SURMODICS, INC. (US) | 2011-10-11 | — | — | US | disclosed |
| US-8021680-B2 | Longitudinal body; polymeric coating of polyalkyl(meth)acrylate and/or aromatic poly(meth)acrylate; and poly(ethylene-co-vinyl acetate); triamcinolone acetonide; drug delivery to eye | SURMODICS, INC. (US) | 2011-09-20 | — | — | US | disclosed |
| US-7976862-B2 | Controlled release bioactive agent delivery device | SURMODICS, INC. (US) | 2011-07-12 | — | — | US | disclosed |
| US-20110054417-A1 | BIOACTIVE AGENT RELEASE COATING AND CONTROLLED HUMIDITY METHOD | SURMODICS, INC. (US) | 2011-03-03 | — | — | US | disclosed |
| US-7833548-B2 | Coating includes the bioactive agent in combination with first polymer component such as polyalkyl(meth)acrylate, polyaryl(meth)acrylate and second polymer component such as poly(ethylene-co-vinyl acetate); for catheters and stents | SURMODICS, INC. (US) | 2010-11-16 | — | — | US | disclosed |
| US-7824704-B2 | Controlled release bioactive agent delivery device | SURMODICS, INC. (US) | 2010-11-02 | — | — | US | disclosed |
| EP-1671624-B1 | Delivery device for a controlled drug release of an active agent into the posterior section of the eye | SURMODICS INC (US) | 2010-08-11 | — | — | EP | disclosed |
| US-20100158799-A1 | METHOD AND COMPOSITION FOR BIOACTIVE AGENT RELEASE IN VIVO | SURMODICS, INC. (US) | 2010-06-24 | — | — | US | disclosed |
| EP-1517714-B1 | BIOACTIVE AGENT RELEASE COATING AND CONTROLLED HUMIDITY METHOD | SURMODICS INC (US) | 2009-07-29 | — | — | EP | disclosed |
| EP-1893144-A1 | MEDICAL DEVICES AND METHODS FOR PRODUCING THE SAME | SurModics, Inc. (US) | 2008-03-05 | — | — | EP | disclosed |
| US-20080031918-A1 | BARRIERS FOR POLYMERIC COATINGS | SURMODICS, INC. | 2008-02-07 | — | — | US | disclosed |
| US-20070248637-A1 | Bioactive agent release coating and controlled humidity method | SURMODICS, INC. | 2007-10-25 | — | — | US | disclosed |
| EP-1567203-B1 | BARRIERS FOR BIOACTIVE AGENT-CONTAINING POLYMERIC COATINGS | SURMODICS INC (US) | 2007-09-26 | — | — | EP | disclosed |
| WO-2006110366-A1 | MEDICAL DEVICES AND METHODS FOR PRODUCING THE SAME | SURMODICS, INC. (US) | 2006-10-19 | — | — | WO | disclosed |
| US-7097850-B2 | Bioactive agent release coating and controlled humidity method | SURMODICS, INC. (US) | 2006-08-29 | — | — | US | disclosed |
| EP-1671624-A1 | Delivery device for a controlled drug release of an active agent into the posterior section of the eye | SurModics, Inc. (US) | 2006-06-21 | — | — | EP | disclosed |
| EP-1633320-A2 | IMPLANTABLE CONTROLLED RELEASE BIOACTIVE AGENT DELIVERY DEVICE | SurModics, Inc. (US) | 2006-03-15 | — | — | EP | disclosed |
| EP-1551469-B1 | BIOACTIVE AGENT RELEASE COATING WITH AROMATIC POLY(METH)ACRYLATES | SURMODICS INC (US) | 2006-03-08 | — | — | EP | disclosed |
| US-20060013835-A1 | Controlled release bioactive agent delivery device | ANDERSON ARON B | 2006-01-19 | — | — | US | disclosed |
| WO-2006002112-A1 | DEVICES, ARTICLES, COATINGS, AND METHODS FOR CONTROLLED ACTIVE AGENT RELEASE | SURMODICS, INC. (US) | 2006-01-05 | — | — | WO | disclosed |
| US-20050287188-A1 | Controlled release bioactive agent delivery device | ANDERSON ARON B | 2005-12-29 | — | — | US | disclosed |
| US-20050281858-A1 | Devices, articles, coatings, and methods for controlled active agent release | Surmodics Coatings, LLC | 2005-12-22 | — | — | US | disclosed |
| US-20050281863-A1 | Controlled release bioactive agent delivery device | ANDERSON ARON B | 2005-12-22 | — | — | US | disclosed |
| US-20050281857-A1 | Methods and reagents for preparing biomolecule-containing coatings | Surmodics Coatings, LLC | 2005-12-22 | — | — | US | disclosed |
| US-20050276837-A1 | Controlled release bioactive agent delivery device | ANDERSON ARON B | 2005-12-15 | — | — | US | disclosed |
| US-20050271703-A1 | Controlled release bioactive agent delivery device | ANDERSON ARON B | 2005-12-08 | — | — | US | disclosed |
| WO-2005115490-A2 | NATURAL BIODEGRADABLE POLYSACCHARIDE COATINGS FOR MEICAL ARTICLES | SURMODICS, INC. (US) | 2005-12-08 | — | — | WO | disclosed |
| US-20050271706-A1 | Controlled release bioactive agent delivery device | ANDERSON ARON B | 2005-12-08 | — | — | US | disclosed |
| US-20050196424-A1 | Medical devices and methods for producing the same | SURMODICS MD, LLC | 2005-09-08 | — | — | US | disclosed |
| EP-1567203-A2 | BARRIERS FOR BIOACTIVE AGENT-CONTAINING POLYMERIC COATINGS | SurModics, Inc. (US) | 2005-08-31 | — | — | EP | disclosed |
| EP-1551469-A1 | BIOACTIVE AGENT RELEASE COATING WITH AROMATIC POLY(METH)ACRYLATES | SurModics, Inc. (US) | 2005-07-13 | — | — | EP | disclosed |
| EP-1534354-A1 | METHOD AND SYSTEM FOR PROVIDING BIOACTIVE AGENT RELEASE COATING | SurModics, Inc. (US) | 2005-06-01 | — | — | EP | disclosed |
| EP-1517714-A1 | BIOACTIVE AGENT RELEASE COATING AND CONTROLLED HUMIDITY METHOD | SurModics, Inc. (US) | 2005-03-30 | — | — | EP | disclosed |
| US-20050019371-A1 | Controlled release bioactive agent delivery device | SURMODICS, INC. | 2005-01-27 | — | — | US | disclosed |
| WO-2004098565-A2 | IMPLANTABLE CONTROLLED RELEASE BIOACTIVE AGENT DELIVERY DEVICE | SURMODICS, INC. (US) | 2004-11-18 | — | — | WO | disclosed |
| WO-2004052420-A2 | BARRIERS FOR BIOACTIVE AGENT-CONTAINING POLYMERIC COATINGS | SURMODICS, INC. (US) | 2004-06-24 | — | — | WO | disclosed |
| US-20040111144-A1 | Barriers for polymeric coatings | Surmodics Coatings, LLC | 2004-06-10 | — | — | US | disclosed |
| WO-2003105920-A1 | METHOD AND SYSTEM FOR PROVIDING BIOACTIVE AGENT RELEASE COATING | SURMODICS, INC. (US) | 2003-12-24 | — | — | WO | disclosed |
| WO-2003105918-A1 | BIOACTIVE AGENT RELEASE COATING WITH AROMATIC POLY(METH)ACRYLATES | SURMODICS, INC. (US) | 2003-12-24 | — | — | WO | disclosed |
| WO-2003105919-A1 | BIOACTIVE AGENT RELEASE COATING AND CONTROLLED HUMIDITY METHOD | SURMODICS, INC. (US) | 2003-12-24 | — | — | WO | disclosed |
| US-20030232087-A1 | Bioactive agent release coating with aromatic poly(meth)acrylates | Surmodics Coatings, LLC | 2003-12-18 | — | — | US | disclosed |
| US-20030232122-A1 | Bioactive agent release coating and controlled humidity method | Surmodics Coatings, LLC | 2003-12-18 | — | — | US | disclosed |
| US-20020188037-A1 | Method and system for providing bioactive agent release coating | Surmodics Coatings, LLC | 2002-12-12 | — | — | US | disclosed |
| US-20020188037-A1 | Method and system for providing bioactive agent release coating | Surmodics Coatings, LLC | 2002-12-12 | — | — | US | disclosed |