SCHEMBL2805922

SCHEMBL2805922

COC1(O)C=CC=CC1C(=O)c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
TSHR P16473 2/20 0.37
EPHX1 P07099 2/20 0.36
ALDH1A1 P00352 3/20 0.35
ALOX15 P16050 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
HSD17B10 Q99714 1/20 0.35
CES1 P23141 2/20 0.35
SRC P12931 1/20 0.35
MAPT P10636 2/20 0.33
HTT P42858 2/20 0.33
CES2 O00748 1/20 0.33
HBB P68871 1/20 0.33
KMT2A Q03164 3/20 0.33
MEN1 O00255 2/20 0.33
GAA P10253 1/20 0.33
MMP9 P14780 1/20 0.33
MMP8 P22894 1/20 0.33
TP53 P04637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7386572 0.84 NPC1 (0.37) NPC1L3MBTL1TSHRALDH1A1ALOX15
SCHEMBL10959754 0.83 NPC1 (0.40) NPC1L3MBTL1TSHREPHX1ALDH1A1
SCHEMBL4635207 0.82 LMNA (0.41) NPC1L3MBTL1TSHRALDH1A1ALOX15
SCHEMBL28442226 0.82 NPC1 (0.40) NPC1L3MBTL1TSHREPHX1ALDH1A1
SCHEMBL17891288 0.81 ELANE (0.42) NPC1L3MBTL1ALDH1A1MAPTMMP9
SCHEMBL9403246 0.80 GAA (0.36) NPC1L3MBTL1TSHRALDH1A1ALOX15
SCHEMBL5150393 0.80 KMT2A (0.40) NPC1L3MBTL1TSHRALDH1A1ALOX15
SCHEMBL820868 0.80 NPC1 (0.37) NPC1L3MBTL1TSHRALDH1A1ALOX15
SCHEMBL28014454 0.80 NPC1 (0.42) NPC1L3MBTL1TSHREPHX1ALDH1A1
SCHEMBL1828048 0.79 L3MBTL1 (0.41) NPC1L3MBTL1TSHREPHX1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160155975-A1 ORGANIC PHOTOELECTRONIC DEVICE AND IMAGE SENSOR SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-06-02 US disclosed
CN-101495557-B Improved processing conditions of polyethylene articles during their preparation by melt processing CLARIANT FINANCE BVI LTD 2012-01-11 CN disclosed
US-20100239621-A1 GEL SHEET AND COSMETIC PREPARATION IN SHEET FORM USING THE SAME FUJIFILM CORPORATION (JP) 2010-09-23 US disclosed
EP-2210583-A1 GEL SHEET AND COSMETIC PREPARATION IN SHEET FORM USING THE SAME FUJIFILM Corporation (JP) 2010-07-28 EP disclosed
CN-101495557-A Improved processing conditions of polyethylene articles during their preparation by melt processing CLARIANT FINANCE BVI LTD (VG) 2009-07-29 CN disclosed
WO-2009038030-A1 GEL SHEET AND SHEET-LIKE COSMETIC MATERIAL USING THE SAME FUJIFILM CORPORATION (JP) 2009-03-26 WO disclosed
US-7190506-B1 Electrochromic device with nanoparticles and UV-absorbers in the protective coating BAYER AKTIENGESELLSCHAFT (DE) 2007-03-13 US disclosed
EP-1027397-B1 ELECTROCHROME POLYMER SYSTEMS BAYER INNOVATION GMBH (DE) 2006-10-18 EP disclosed
US-6569361-B1 Polycondensation or polyaddition of electrochromic monomers are used in devices for variable transparency BAYER AKTIENGESELLSCHAFT (DE) 2003-05-27 US disclosed
EP-1027397-A1 ELECTROCHROME POLYMER SYSTEMS Bayer Aktiengesellschaft (DE) 2000-08-16 EP disclosed
WO-1999002621-A1 ELECTROCHROME POLYMER SYSTEMS BAYER AKTIENGESELLSCHAFT (DE) 1999-01-21 WO disclosed
EP-0728327-A1 PROCESS FOR MAKING AN ARRAY OF TAPERED PHOTOPOLYMERIZED WAVEGUIDES AlliedSignal Inc. (US) 1996-08-28 EP disclosed
WO-1995013567-A1 PROCESS FOR MAKING AN ARRAY OF TAPERED PHOTOPOLYMERIZED WAVEGUIDES ALLIEDSIGNAL INC. (US) 1995-05-18 WO disclosed
EP-0412570-A2 Light- and heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 1991-02-13 EP disclosed
US-4663088-A COSMETIC SUNSCREENS L'OREAL (FR) 1987-05-05 US disclosed
US-4654434-A SUN FILTERS L'OREAL (FR) 1987-03-31 US disclosed
US-4585597-A 3-benzylidene-camphors, process for their preparation and their use in protection against UV rays L'OREAL (FR) 1986-04-29 US disclosed
US-4379871-A Process for the production of carbon black containing pigment-synthetic resin concentrates DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) 1983-04-12 US disclosed