Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 4/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 4/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 4/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | STAT6 | P42226 | 1/20 | 0.35 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5608457 | 0.84 | CRHBP (0.39) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL12017088 | 0.80 | — | — | |
| SCHEMBL5803834 | 0.77 | PKM (0.45) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL5608320 | 0.75 | TSHR (0.39) | LMNATSHRCRHBPCRHR2EPHX2 | |
| SCHEMBL1497436 | 0.75 | NPC1 (0.31) | — | |
| SCHEMBL8789410 | 0.75 | — | — | |
| SCHEMBL5191921 | 0.75 | PKM (0.48) | CRHBPCRHR2ALDH1A1 | |
| SCHEMBL5608271 | 0.71 | PKM (0.45) | LMNAGAAPOLBTHRBSMN1; SMN2 | |
| SCHEMBL6058601 | 0.71 | ALDH1A1 (0.40) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL28118949 | 0.71 | EPHX2 (0.39) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 121 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119661365-A | Novel method for producing amantadine hydrochloride | 李果 | 2025-03-21 | — | — | CN | claimed |
| CN-119661364-A | Method for producing high-purity amantadine | 李果 | 2025-03-21 | — | — | CN | claimed |
| CN-119661366-A | Preparation method and application of amantadine carbonate | 李果 | 2025-03-21 | — | — | CN | claimed |
| CN-112479896-A | Method for synthesizing and preparing amantadine dry product | 天津民祥药业有限公司 | 2021-03-12 | — | — | CN | claimed |
| US-9301950-B2 | Adamantane analogs | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2016-04-05 | — | — | US | claimed |
| US-20120270917-A1 | ADAMANTANE ANALOGS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2012-10-25 | — | — | US | claimed |
| WO-2011022191-A1 | ADAMANTANE ANALOGS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2011-02-24 | — | — | WO | claimed |
| JP-10036324-A | — | — | None | — | — | JP | disclosed |
| CN-119661364-A | Method for producing high-purity amantadine | 李果 | 2025-03-21 | — | — | CN | disclosed |
| CN-119661366-A | Preparation method and application of amantadine carbonate | 李果 | 2025-03-21 | — | — | CN | disclosed |
| CN-119661365-A | Novel method for producing amantadine hydrochloride | 李果 | 2025-03-21 | — | — | CN | disclosed |
| CN-115785465-B | Multi-responsiveness polarized light pigment particle and preparation method and application thereof | 现代纺织技术创新中心(鉴湖实验室) | 2023-08-18 | — | — | CN | disclosed |
| CN-114195787-A | 2-nitro-2-azaadamantane-4, 6, 8-triol trinitrate and preparation method thereof | 南京理工大学 | 2022-03-18 | — | — | CN | disclosed |
| EP-0990631-A1 | PROCESS FOR COOXIDIZING ORGANIC COMPOUNDS, PROCESS FOR PRODUCING EPOXY COMPOUNDS AND PROCESS FOR PRODUCING ESTERS OR LACTONES | Daicel Chemical Industries, Ltd. (JP) | 2000-04-05 | — | — | EP | disclosed |
| US-5998661-A | Preparations of organic nitro compounds through mixed oxidizing agents | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1999-12-07 | — | — | US | disclosed |
| EP-0927711-A1 | ADAMANTANE DERIVATIVES AND PROCESS FOR PRODUCING THEM | Daicel Chemical Industries, Ltd. (JP) | 1999-07-07 | — | — | EP | disclosed |
| EP-0915077-A1 | POLYMERIZABLE ADAMANTANE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | Daicel Chemical Industries, Ltd. (JP) | 1999-05-12 | — | — | EP | disclosed |
| EP-0897747-A1 | NITRATION OR CARBOXYLATION CATALYSTS | Daicel Chemical Industries, Ltd. (JP) | 1999-02-24 | — | — | EP | disclosed |
| JP-H1036324-A | PRODUCTION OF 1-NITROADAMANTANE DERIVATIVE | NISSAN CHEM IND LTD | 1998-02-10 | — | — | JP | disclosed |
| US-4329522-A | 1,3,5,7-Tetranitroadamantane and process for preparing same | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1982-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120270917-A1 | ADAMANTANE ANALOGS | HAVCR2, ADORA2A, ADORA1 | GRIN2D 1720/4885GRIN3B 556/4885GRIN1 570/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.