Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | FPR1 | P21462 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8755381 | 0.92 | MEN1 (0.40) | TSHRGABRA1GABRB2CYP3A4CYP2D6 | |
| SCHEMBL15375368 | 0.83 | FABP4 (0.40) | TSHRGABRA1GABRB2MAPTNPSR1 | |
| SCHEMBL15375461 | 0.83 | MAPT (0.46) | TSHRMAPTNPSR1L3MBTL1MEN1 | |
| SCHEMBL27836988 | 0.82 | CYSLTR2 (0.43) | TSHRCYP3A4CYP2D6 | |
| SCHEMBL1199394 | 0.81 | TSHR (0.39) | TSHRL3MBTL1 | |
| SCHEMBL1200211 | 0.81 | TSHR (0.39) | TSHRMEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL1199361 | 0.81 | TSHR (0.39) | TSHRMAPTNPSR1L3MBTL1MEN1 | |
| SCHEMBL1200951 | 0.80 | TSHR (0.41) | TSHRMAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL1199980 | 0.80 | TSHR (0.41) | TSHRL3MBTL1 | |
| SCHEMBL11602112 | 0.79 | CYP3A4 (0.51) | TSHRGABRA1GABRB2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0527553-B1 | Process for producing r(-)-mandelic acid and derivative thereof | NITTO CHEMICAL INDUSTRY CO LTD (JP) | 1997-05-07 | — | — | EP | claimed |
| US-5296373-A | Stereoselective hydrolysis of mandelonitrile in neutral or basic aqueous medium | NITTO CHEMICAL INDUSTRY CO., LTD. (JP) | 1994-03-22 | — | — | US | claimed |
| EP-0527553-A1 | Process for producing r(-)-mandelic acid and derivative thereof | NITTO CHEMICAL INDUSTRY CO., LTD. (JP) | 1993-02-17 | — | — | EP | claimed |
| CN-102007095-B | Method for producing optically active cyanohydrin compound | SUMITOMO CHEMICAL CO.,LTD. (JP) | 2014-10-08 | — | — | CN | disclosed |
| US-8309753-B2 | Method for producing optically active cyanohydrin compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-11-13 | — | — | US | disclosed |
| CN-102007095-A | Method for producing optically active cyanohydrin compound | SUMITOMO CHEMICAL CO | 2011-04-06 | — | — | CN | disclosed |
| US-20110034718-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE CYANOHYDRIN COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-02-10 | — | — | US | disclosed |
| EP-2264005-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE CYANOHYDRIN COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2010-12-22 | — | — | EP | disclosed |
| US-5296373-A | Stereoselective hydrolysis of mandelonitrile in neutral or basic aqueous medium | NITTO CHEMICAL INDUSTRY CO., LTD. (JP) | 1994-03-22 | — | — | US | disclosed |
| EP-0527553-A1 | Process for producing r(-)-mandelic acid and derivative thereof | NITTO CHEMICAL INDUSTRY CO., LTD. (JP) | 1993-02-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110034718-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE CYANOHYDRIN COMPOUND | CBR3, ACSL3, CCNL2 | TSHR 4501/4885GABRA1 4514/4885GABRB2 4598/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.