SCHEMBL15375461

SCHEMBL15375461

CCc1ccccc1OCc1ccccc1C(O)C#N

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.46
L3MBTL1 Q9Y468 3/20 0.46
NPSR1 Q6W5P4 1/20 0.46
NISCH Q9Y2I1 1/20 0.41
FABP4 P15090 2/20 0.40
FABP5 Q01469 2/20 0.40
ADRB2 P07550 1/20 0.39
ADRB1 P08588 1/20 0.39
ADRB3 P13945 1/20 0.39
ATM Q13315 2/20 0.38
HPGD P15428 1/20 0.38
MCL1 Q07820 1/20 0.38
SGMS2 Q8NHU3 7/20 0.37
ALDH1A1 P00352 5/20 0.37
LMNA P02545 2/20 0.37
PTGDR2 Q9Y5Y4 1/20 0.37
MEN1 O00255 1/20 0.37
GAA P10253 1/20 0.37
THRB P10828 1/20 0.37
RECQL P46063 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15375308 0.87 MAPT (0.35) MAPTL3MBTL1NPSR1FABP4FABP5
SCHEMBL15375397 0.87 FFAR4 (0.35) MAPTL3MBTL1NPSR1FABP4FABP5
SCHEMBL15375360 0.86 PTGDR2 (0.47) MAPTL3MBTL1NPSR1FABP4FABP5
SCHEMBL1900216 0.86 ALOX15 (0.44) MAPTADRB2ADRB1ADRB3HPGD
SCHEMBL28038432 0.86 ALOX15 (0.44) MAPTADRB2ADRB1ADRB3HPGD
SCHEMBL15375368 0.86 FABP4 (0.40) MAPTL3MBTL1NPSR1FABP4FABP5
SCHEMBL15375445 0.86 NISCH (0.43) L3MBTL1NISCHFABP4FABP5ADRB2
SCHEMBL1200548 0.83 TSHR (0.45) MAPTL3MBTL1NPSR1ALDH1A1LMNA
SCHEMBL15375378 0.82 RXRA (0.44) MAPTL3MBTL1NPSR1NISCHFABP4
SCHEMBL15375379 0.82 SGMS2 (0.38) MAPTNPSR1FABP4FABP5SGMS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2682382-B1 Method for Producing Phenylacetamide Compound SUMITOMO CHEMICAL CO (JP) 2016-11-23 EP disclosed
EP-2662352-B1 Method for Producing Phenylacetamide Compound SUMITOMO CHEMICAL CO (JP) 2016-11-09 EP disclosed
EP-2397459-B1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND SUMITOMO CHEMICAL CO (JP) 2015-12-16 EP disclosed
CN-103641731-B The manufacture method of phenylacetyl amine compound SUMITOMO CHEMICAL CO., LTD. (JP) 2015-10-28 CN disclosed
CN-103588657-A Method for producing phenylacetamide compound SUMITOMO CHEMICAL CO 2014-02-19 CN disclosed
EP-2682382-A2 Method for Producing Phenylacetamide Compound Sumitomo Chemical Company, Limited (JP) 2014-01-08 EP disclosed
US-8624062-B2 Method for producing phenylacetamide compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-01-07 US disclosed
EP-2662352-A2 Method for Producing Phenylacetamide Compound Sumitomo Chemical Company, Limited (JP) 2013-11-13 EP disclosed
EP-2397459-A1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND Sumitomo Chemical Company, Limited (JP) 2011-12-21 EP disclosed
US-20110295035-A1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110295035-A1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND MRPL21, AADAC, ARSA MAPT 3967/4885L3MBTL1 2775/4885NPSR1 1234/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.