Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.78 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.78 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.57 |
| ▸ | FEN1 | P39748 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2925459 | 0.82 | NPC1 (0.71) | HPGDL3MBTL1RAB9ALMNAMEN1 | |
| SCHEMBL5161077 | 0.79 | LMNA (0.63) | HPGDL3MBTL1RAB9APOLBERCC5 | |
| SCHEMBL13685740 | 0.78 | HPGD (0.60) | HPGDL3MBTL1RAB9ALMNAMEN1 | |
| SCHEMBL6301755 | 0.78 | MEN1 (0.67) | HPGDL3MBTL1RAB9APOLBERCC5 | |
| SCHEMBL711360 | 0.77 | RAB9A (0.75) | HPGDL3MBTL1RAB9APOLBERCC5 | |
| SCHEMBL3087061 | 0.77 | GAA (0.73) | HPGDL3MBTL1RAB9ALMNAMEN1 | |
| SCHEMBL19399121 | 0.77 | HPGD (0.68) | HPGDL3MBTL1RAB9APOLBERCC5 | |
| SCHEMBL3917581 | 0.77 | GAA (0.68) | L3MBTL1RAB9APOLBLMNAMEN1 | |
| SCHEMBL1199497 | 0.76 | ALDH1A1 (0.74) | HPGDRAB9ALMNAMEN1KMT2A | |
| SCHEMBL1515726 | 0.76 | NPC1 (0.62) | HPGDL3MBTL1RAB9APOLBERCC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102321066-B | Method for producing aryl-aminopropanols | SALTIGO GMBH | 2014-07-23 | — | — | CN | disclosed |
| CN-1445224-B | Process for preparing arylaminopropanols | SALTIGO GMBH | 2012-07-11 | — | — | CN | disclosed |
| CN-102321066-A | The method for preparing the arylamino propyl alcohol | SALTIGO GMBH | 2012-01-18 | — | — | CN | disclosed |
| US-7893281-B2 | Process for preparing arylaminopropanols | LANXESS DEUTSCHLAND GMBH (DE) | 2011-02-22 | — | — | US | disclosed |
| US-20090286997-A1 | PROCESS FOR PREPARING ARYLAMINOPROPANOLS | LANXESS DEUTSCHLAND GMBH (DE) | 2009-11-19 | — | — | US | disclosed |
| US-7582776-B2 | Process for preparing arylaminopropanols | LANXESS DEUTSCHLAND GMBH (DE) | 2009-09-01 | — | — | US | disclosed |
| EP-1346977-B1 | Method for producing aryl-aminopropanols | SALTIGO GMBH (DE) | 2009-07-22 | — | — | EP | disclosed |
| US-20080262247-A1 | Process for preparing arylaminopropanols | ECKERT MARKUS | 2008-10-23 | — | — | US | disclosed |
| US-7169938-B2 | Process for preparing arylaminopropanols | LANXESS DEUTSCHLAND GMBH (DE) | 2007-01-30 | — | — | US | disclosed |
| US-20030225153-A1 | Process for preparing arylaminopropanols | LANXESS DEUTSCHLAND GMBH (DE) | 2003-12-04 | — | — | US | disclosed |
| CN-1445224-A | Process for preparing arylaminopropanols | BAYER AG (DE) | 2003-10-01 | — | — | CN | disclosed |
| EP-1346977-A1 | Method for producing aryl-aminopropanols | Bayer Aktiengesellschaft (DE) | 2003-09-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030225153-A1 | Process for preparing arylaminopropanols | AHR, CYP1A1, CYP1A2 | HPGD 1504/4885L3MBTL1 4597/4885RAB9A 3297/4885 |
| US-20090286997-A1 | PROCESS FOR PREPARING ARYLAMINOPROPANOLS | AHR, CYP1A1, CYP1A2 | HPGD 1504/4885L3MBTL1 4597/4885RAB9A 3297/4885 |
| US-20080262247-A1 | Process for preparing arylaminopropanols | CYP1A1, CYP1A2, AHR | HPGD 1119/4885L3MBTL1 4570/4885RAB9A 3050/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.