Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 11/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 9/20 | 0.53 |
| ▸ | KIF11 | P52732 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TYR | P14679 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | ESRRG | P62508 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13609942 | 0.94 | ESR1 (0.59) | ESR1ESR2CYP3A4LMNATYR | |
| SCHEMBL12004409 | 0.92 | ESR1 (0.60) | ESR1ESR2KIF11CYP3A4LMNA | |
| SCHEMBL16675611 | 0.90 | CA1 (0.56) | ESR1ESR2ARMEN1KMT2A | |
| SCHEMBL3649814 | 0.89 | ESR1 (0.61) | ESR1ESR2CYP3A4LMNATYR | |
| SCHEMBL2618675 | 0.88 | ESR1 (0.55) | ESR1ESR2CYP3A4LMNATYR | |
| SCHEMBL30899192 | 0.87 | ESR2 (0.74) | ESR1ESR2CYP3A4LMNATYR | |
| SCHEMBL12004872 | 0.85 | ESR1 (0.70) | ESR1ESR2KIF11CYP3A4LMNA | |
| SCHEMBL10772499 | 0.85 | ESR1 (0.70) | ESR1ESR2KIF11CYP3A4LMNA | |
| SCHEMBL26136547 | 0.85 | ESR1 (0.70) | ESR1ESR2KIF11CYP3A4LMNA | |
| SCHEMBL12005115 | 0.84 | MAOB (0.46) | ESR1ESR2CYP3A4LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8816135-B2 | Trisphenol compound | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2014-08-26 | — | — | US | disclosed |
| US-8816135-B2 | Trisphenol compound | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2014-08-26 | — | — | US | disclosed |
| US-8816135-B2 | Trisphenol compound | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2014-08-26 | — | — | US | disclosed |
| US-20120220805-A1 | NOVEL TRISPHENOL COMPUND | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2012-08-30 | — | — | US | disclosed |
| US-20120220805-A1 | NOVEL TRISPHENOL COMPUND | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2012-08-30 | — | — | US | disclosed |
| US-20120220805-A1 | NOVEL TRISPHENOL COMPUND | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2012-08-30 | — | — | US | disclosed |
| WO-2011030835-A1 | NOVEL TRISPHENOL COMPOUND | 本州化学工業株式会社 (JP) | 2011-03-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120220805-A1 | NOVEL TRISPHENOL COMPUND | NCOR1, NCOR2, NCOA1 | ESR1 40/4885ESR2 18/4885KIF11 3967/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.