SCHEMBL30899192

SCHEMBL30899192

Cc1cc(C(C)(c2ccccc2)c2ccc(O)cc2)cc(C)c1O

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 8/20 0.74
ESR1 P03372 8/20 0.74
CYP3A4 P08684 2/20 0.57
ALDH1A1 P00352 2/20 0.57
LMNA P02545 2/20 0.43
TYR P14679 1/20 0.43
AR P10275 1/20 0.43
HPGD P15428 1/20 0.43
TSHR P16473 1/20 0.43
SLC6A2 P23975 1/20 0.43
SLC6A4 P31645 1/20 0.43
HTR6 P50406 1/20 0.43
ESRRG P62508 1/20 0.43
SLC6A3 Q01959 1/20 0.43
HSD17B10 Q99714 1/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
TTR P02766 1/20 0.43
ALOX5 P09917 1/20 0.43
PTGS1 P23219 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5086131 0.93 ESR1 (0.69) ESR2ESR1CYP3A4ALDH1A1LMNA
SCHEMBL2004560 0.92 ESR1 (0.66) ESR2ESR1CYP3A4ALDH1A1LMNA
SCHEMBL13609942 0.92 ESR1 (0.59) ESR2ESR1CYP3A4ALDH1A1LMNA
SCHEMBL23059478 0.88 ESR1 (0.87) ESR2ESR1CYP3A4ALDH1A1LMNA
SCHEMBL12006459 0.87 ESR1 (0.53) ESR2ESR1CYP3A4ALDH1A1LMNA
SCHEMBL3649814 0.87 ESR1 (0.61) ESR2ESR1CYP3A4ALDH1A1LMNA
SCHEMBL8031149 0.86 ESR1 (1.00) ESR2ESR1CYP3A4ALDH1A1LMNA
SCHEMBL27277 0.86 ESR1 (1.00) ESR2ESR1CYP3A4ALDH1A1LMNA
SCHEMBL2618675 0.86 ESR1 (0.55) ESR2ESR1CYP3A4ALDH1A1LMNA
Methane SCHEMBL16667289 0.84 ESR1 (0.95) ESR2ESR1CYP3A4ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113646052-B Reversible thermochromic composition, reversible thermochromic microcapsule pigment, and writing instrument 百乐墨水株式会社 2024-05-17 CN disclosed