SCHEMBL120087

SCHEMBL120087

CC1CCC(C(C)C)C(C(=O)NC(C)(C)C)C1

nearest known ligand 0.58

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 3/20 0.58
TRPM8 Q7Z2W7 7/20 0.56
TRPA1 O75762 2/20 0.44
TRPV1 Q8NER1 5/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15016269 1.00 EPHX1 (0.58) EPHX1TRPM8TRPA1TRPV1
SCHEMBL29177116 1.00 EPHX1 (0.58) EPHX1TRPM8TRPA1TRPV1
SCHEMBL15016267 1.00 EPHX1 (0.58) EPHX1TRPM8TRPA1TRPV1
SCHEMBL3228965 1.00 EPHX1 (0.58) EPHX1TRPM8TRPA1TRPV1
SCHEMBL930592 1.00 EPHX1 (0.58) EPHX1TRPM8TRPA1TRPV1
SCHEMBL14072907 0.88 EPHX1 (0.44) EPHX1TRPM8TRPA1TRPV1
SCHEMBL14072905 0.88 EPHX1 (0.44) EPHX1TRPM8TRPA1TRPV1
SCHEMBL469472 0.85 TRPM8 (0.54) EPHX1TRPM8TRPA1TRPV1
SCHEMBL18287146 0.85 TRPM8 (0.58) EPHX1TRPM8TRPA1TRPV1
SCHEMBL18287162 0.84 TRPM8 (0.53) EPHX1TRPM8TRPA1TRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1176 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4144230-B1 CHILLED POUCH MATERIAL FOR NICOTINE POUCH JT INT SA (CH) 2024-08-07 EP claimed
CN-110869365-B Cooling composition 弗门尼舍有限公司 2024-03-29 CN claimed
EP-4268814-A2 PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF DRY EYE Universidad Miguel Hernández De Elche (ES) 2023-11-01 EP claimed
CN-115919958-A Cooling agent and production method thereof 南通亚香食品科技有限公司 2023-04-07 CN claimed
US-20230077134-A1 Chilled Pouch Material for Nicotine Pouch JT INTERNATIONAL SA (CH) 2023-03-09 US claimed
EP-4144230-A1 CHILLED POUCH MATERIAL FOR NICOTINE POUCH JT International SA (CH) 2023-03-08 EP claimed
US-20220331344-A1 ORAL FORMULATIONS OF PSYCHOTROPIC MACROFUNGUS BOTANICAL EXTRACTS WITH MOUTHFEEL EXPERIENCE ENHANCERS CHICAGO ATLANTIC ADMIN, LLC 2022-10-20 US claimed
CN-109832656-B Cool functional reconstituted tobacco and preparation method and application thereof 云南中烟工业有限责任公司 2022-02-01 CN claimed
CN-113133950-A Composition and solution for refreshing and relieving fatigue and application thereof 深圳全棉时代科技有限公司 2021-07-20 CN claimed
US-20210212983-A1 ORAL CANNABINOID DELIVERY FORMULATIONS WITH MOUTHFEEL EXPERIENCE ENHANCERS CHICAGO ATLANTIC ADMIN, LLC 2021-07-15 US claimed
US-20040253191-A1 Breath Freshening and Oral Cleansing Product WM. WRIGLEY JR. COMPANY 2004-12-16 US claimed
US-20040253189-A1 Breath Freshening and Oral Cleansing Product Using Geraniol WM. WRIGLEY JR. COMPANY 2004-12-16 US claimed
WO-2004019867-A2 BREATH FRESHENING AND ORAL CLEANSING PRODUCT USING CARDAMOM OIL WM. WRIGLEY JR. COMPANY (US) 2004-03-11 WO claimed
WO-2004019800-A2 BREATH FRESHENING AND ORAL CLEANSING PRODUCT WM. WRIGLEY JR. COMPANY (US) 2004-03-11 WO claimed
WO-2004019870-A2 BREATH FRESHENING AND ORAL CLEANSING PRODUCT USING SALICYLALDEHYDE WM. WRIGLEY JR. COMPANY (US) 2004-03-11 WO claimed
WO-2004019922-A1 BREATH FRESHENING AND ORAL CLEANSING PRODUCT USING CITRAL WM. WRIGLEY JR. COMPANY (US) 2004-03-11 WO claimed
WO-2004019802-A2 BREATH FRESHENING AND ORAL CLEANSING PRODUCT USING CARVACROL WM. WRIGLEY JR. COMPANY (US) 2004-03-11 WO claimed
WO-2004019871-A2 BREATH FRESHENING AND ORAL CLEANSING PRODUCT USING GERANIOL WM. WRIGLEY JR. COMPANY (US) 2004-03-11 WO claimed
US-4350832-A Synthesis of N-t-butyl-p-menthane-3-carboxamide PHILIP MORRIS, INCORPORATED (US) 1982-09-21 US claimed
US-4060091-A N-SUBSTITUTED P-MENTHANE CARBOXAMID WILKINSON SWORD LIMITED (EN) 1977-11-29 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220331344-A1 ORAL FORMULATIONS OF PSYCHOTROPIC MACROFUNGUS BOTANICAL EXTRACTS WITH MOUTHFEEL EXPERIENCE ENHANCERS MB, MLEC, NISCH EPHX1 3871/4885TRPM8 1381/4885TRPA1 2103/4885
US-20210212983-A1 ORAL CANNABINOID DELIVERY FORMULATIONS WITH MOUTHFEEL EXPERIENCE ENHANCERS CNR2, CNR1, CPNE4 EPHX1 2098/4885TRPM8 46/4885TRPA1 339/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.