SCHEMBL1201002

SCHEMBL1201002

N#CC(O)c1ccccc1COc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.43
KDM4E B2RXH2 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
FFAR1 O14842 2/20 0.41
PTPRC P08575 1/20 0.41
PTPN1 P18031 1/20 0.41
MAOB P27338 2/20 0.40
LMNA P02545 1/20 0.40
ALDH1A1 P00352 1/20 0.39
RECQL P46063 1/20 0.39
NR4A2 P43354 2/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
F2 P00734 1/20 0.38
PRSS1 P07477 1/20 0.38
PRSS2 P07478 1/20 0.38
PRSS3 P35030 1/20 0.38
TMPRSS6 Q8IU80 1/20 0.38
ST14 Q9Y5Y6 1/20 0.38
SLC6A2 P23975 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27854360 1.00 TSHR (0.43) TSHRKDM4ESMN1; SMN2FFAR1PTPRC
SCHEMBL15375563 0.88 FFAR1 (0.41) KDM4EFFAR1PTPRCPTPN1MAOB
SCHEMBL28038134 0.88 FFAR1 (0.41) KDM4EFFAR1PTPRCPTPN1MAOB
SCHEMBL15375483 0.86 RXRA (0.41) TSHRKDM4ESMN1; SMN2FFAR1MAOB
SCHEMBL28810581 0.86 RXRA (0.41) TSHRKDM4ESMN1; SMN2FFAR1MAOB
SCHEMBL15375581 0.86 FFAR1 (0.41) KDM4EFFAR1MAOBNPC1RAB9A
SCHEMBL15375511 0.84 POLB (0.41) TSHRSMN1; SMN2MAOBLMNANR4A2
SCHEMBL1899781 0.84 KMT2A (0.43) TSHRSMN1; SMN2MAOBLMNAALDH1A1
SCHEMBL28038080 0.84 KMT2A (0.43) TSHRSMN1; SMN2MAOBLMNAALDH1A1
SCHEMBL27952304 0.84 SMN1; SMN2 (0.35) TSHRKDM4ESMN1; SMN2MAOBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2325161-B1 METHOD FOR PRODUCING ALPHA-HYDROXYESTER COMPOUND SUMITOMO CHEMICAL CO (JP) 2018-07-25 EP disclosed
EP-2682382-B1 Method for Producing Phenylacetamide Compound SUMITOMO CHEMICAL CO (JP) 2016-11-23 EP disclosed
EP-2662352-B1 Method for Producing Phenylacetamide Compound SUMITOMO CHEMICAL CO (JP) 2016-11-09 EP disclosed
CN-102131761-B Process for producing alpha-hydroxy ester compound 住友化学株式会社 2016-09-28 CN disclosed
EP-2397459-B1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND SUMITOMO CHEMICAL CO (JP) 2015-12-16 EP disclosed
CN-103641731-B The manufacture method of phenylacetyl amine compound SUMITOMO CHEMICAL CO., LTD. (JP) 2015-10-28 CN disclosed
CN-102007095-B Method for producing optically active cyanohydrin compound SUMITOMO CHEMICAL CO.,LTD. (JP) 2014-10-08 CN disclosed
CN-103588657-A Method for producing phenylacetamide compound SUMITOMO CHEMICAL CO 2014-02-19 CN disclosed
EP-2682382-A2 Method for Producing Phenylacetamide Compound Sumitomo Chemical Company, Limited (JP) 2014-01-08 EP disclosed
US-8624062-B2 Method for producing phenylacetamide compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-01-07 US disclosed
US-8309753-B2 Method for producing optically active cyanohydrin compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-11-13 US disclosed
US-8299288-B2 Method for producing α-hydroxyester compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-30 US disclosed
EP-2397459-A1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND Sumitomo Chemical Company, Limited (JP) 2011-12-21 EP disclosed
US-20110295035-A1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-01 US disclosed
CN-102131761-A Process for producing alpha-hydroxy ester compound SUMITOMO CHEMICAL CO 2011-07-20 CN disclosed
US-20110144372-A1 METHOD FOR PRODUCING a-HYDROXYESTER COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-06-16 US disclosed
EP-2325161-A1 METHOD FOR PRODUCING -HYDROXYESTER COMPOUND Sumitomo Chemical Company, Limited (JP) 2011-05-25 EP disclosed
CN-102007095-A Method for producing optically active cyanohydrin compound SUMITOMO CHEMICAL CO 2011-04-06 CN disclosed
US-20110034718-A1 METHOD FOR PRODUCING OPTICALLY ACTIVE CYANOHYDRIN COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-02-10 US disclosed
EP-2264005-A1 METHOD FOR PRODUCING OPTICALLY ACTIVE CYANOHYDRIN COMPOUND Sumitomo Chemical Company, Limited (JP) 2010-12-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110144372-A1 METHOD FOR PRODUCING a-HYDROXYESTER COMPOUND CYP17A1, CYP21A2, HSD11B2 TSHR 4022/4885KDM4E 3286/4885SMN1; SMN2 4858/4885
US-20110034718-A1 METHOD FOR PRODUCING OPTICALLY ACTIVE CYANOHYDRIN COMPOUND CBR3, ACSL3, CCNL2 TSHR 4501/4885KDM4E 1728/4885SMN1; SMN2 2884/4885
US-20110295035-A1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND MRPL21, AADAC, ARSA TSHR 1240/4885KDM4E 2619/4885SMN1; SMN2 4638/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.