SCHEMBL15375581

SCHEMBL15375581

CCc1ccc(OCc2ccccc2C(O)C#N)cc1

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 2/20 0.41
RXRA P19793 1/20 0.40
RXRB P28702 1/20 0.40
MAOB P27338 4/20 0.40
FFAR4 Q5NUL3 1/20 0.39
RAB9A P51151 3/20 0.38
NPC1 O15118 2/20 0.38
KMT2A Q03164 1/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
HSP90AA1 P07900 1/20 0.37
CYP2A6 P11509 1/20 0.37
PPARG P37231 1/20 0.36
MAPT P10636 2/20 0.36
BCHE P06276 1/20 0.36
KDM4E B2RXH2 1/20 0.36
SCN9A Q15858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28038134 0.86 FFAR1 (0.41) FFAR1MAOBFFAR4RAB9ANPC1
SCHEMBL15375563 0.86 FFAR1 (0.41) FFAR1MAOBFFAR4RAB9ANPC1
SCHEMBL1201002 0.86 TSHR (0.43) FFAR1MAOBRAB9ANPC1KDM4E
SCHEMBL27854360 0.86 TSHR (0.43) FFAR1MAOBRAB9ANPC1KDM4E
SCHEMBL15375483 0.84 RXRA (0.41) FFAR1RXRARXRBMAOBFFAR4
SCHEMBL28810581 0.84 RXRA (0.41) FFAR1RXRARXRBMAOBFFAR4
SCHEMBL15375511 0.83 POLB (0.41) RXRARXRBMAOBRAB9ANPC1
SCHEMBL15375397 0.82 FFAR4 (0.35) FFAR1FFAR4L3MBTL1MAPT
SCHEMBL15375308 0.82 MAPT (0.35) FFAR1FFAR4RAB9ANPC1L3MBTL1
SCHEMBL15375461 0.81 MAPT (0.46) KMT2AL3MBTL1TDP1MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2682382-B1 Method for Producing Phenylacetamide Compound SUMITOMO CHEMICAL CO (JP) 2016-11-23 EP disclosed
EP-2662352-B1 Method for Producing Phenylacetamide Compound SUMITOMO CHEMICAL CO (JP) 2016-11-09 EP disclosed
EP-2397459-B1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND SUMITOMO CHEMICAL CO (JP) 2015-12-16 EP disclosed
CN-103641731-B The manufacture method of phenylacetyl amine compound SUMITOMO CHEMICAL CO., LTD. (JP) 2015-10-28 CN disclosed
CN-103588657-A Method for producing phenylacetamide compound SUMITOMO CHEMICAL CO 2014-02-19 CN disclosed
EP-2682382-A2 Method for Producing Phenylacetamide Compound Sumitomo Chemical Company, Limited (JP) 2014-01-08 EP disclosed
US-8624062-B2 Method for producing phenylacetamide compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-01-07 US disclosed
EP-2662352-A2 Method for Producing Phenylacetamide Compound Sumitomo Chemical Company, Limited (JP) 2013-11-13 EP disclosed
EP-2397459-A1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND Sumitomo Chemical Company, Limited (JP) 2011-12-21 EP disclosed
US-20110295035-A1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110295035-A1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND MRPL21, AADAC, ARSA FFAR1 3308/4885RXRA 1438/4885RXRB 2062/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.