Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 3/20 | 0.45 |
| ▸ | BRAF | P15056 | 2/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.42 |
| ▸ | CDK8 | P49336 | 3/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.41 |
| ▸ | RAF1 | P04049 | 2/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PLA2G7 | Q13093 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15195568 | 0.87 | BRAF (0.46) | POLBKDRBRAFSCN9ACDK8 | |
| SCHEMBL16976170 | 0.82 | SCN9A (0.43) | KDRBRAFSCN9ACDK8SCN5A | |
| SCHEMBL1201593 | 0.80 | BRAF (0.44) | POLBKDRBRAFSCN9ASCN5A | |
| SCHEMBL16976165 | 0.79 | SCN9A (0.41) | KDRBRAFSCN9ACDK8SCN5A | |
| SCHEMBL12878814 | 0.78 | BRAF (0.41) | KDM4EKDRBRAFSCN9ASCN5A | |
| SCHEMBL1201822 | 0.77 | KDM4E (0.50) | POLBKDM4EKDRBRAFCDK8 | |
| SCHEMBL12878911 | 0.75 | BRAF (0.41) | KDRBRAFSCN9ASCN5ARAF1 | |
| SCHEMBL15195551 | 0.75 | KDM4E (0.47) | POLBKDM4EKDRBRAFSCN9A | |
| SCHEMBL6511184 | 0.74 | MAOA (0.50) | BRAFSCN9ACDK8PIK3CARAF1 | |
| SCHEMBL14656102 | 0.74 | CDK8 (0.67) | KDRBRAFCDK8PIK3CARAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9096525-B2 | Iminipyridine derivatives and their uses as microbiocides | SYNGENTA CROP PROTECTION, LLC (US) | 2015-08-04 | — | — | US | disclosed |
| US-9096525-B2 | Iminipyridine derivatives and their uses as microbiocides | SYNGENTA CROP PROTECTION, LLC (US) | 2015-08-04 | — | — | US | disclosed |
| US-9096525-B2 | Iminipyridine derivatives and their uses as microbiocides | SYNGENTA CROP PROTECTION, LLC (US) | 2015-08-04 | — | — | US | disclosed |
| US-20130338105-A1 | IMINIPYRIDINE DERIVATIVES AND THEIR USES AS MICROBIOCIDES | SYNGENTA CROP PROTECTION LLC (US) | 2013-12-19 | — | — | US | disclosed |
| US-8513286-B2 | Iminipyridine derivatives and their uses as microbiocides | SYNGENTA CROP PROTECTION LLC (US) | 2013-08-20 | — | — | US | disclosed |
| US-8513286-B2 | Iminipyridine derivatives and their uses as microbiocides | SYNGENTA CROP PROTECTION LLC (US) | 2013-08-20 | — | — | US | disclosed |
| US-8513286-B2 | Iminipyridine derivatives and their uses as microbiocides | SYNGENTA CROP PROTECTION LLC (US) | 2013-08-20 | — | — | US | disclosed |
| US-20110046088-A1 | IMINIPYRIDINE DERIVATIVES AND THEIR USES AS MICROBIOCIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2011-02-24 | — | — | US | disclosed |
| US-20110046088-A1 | IMINIPYRIDINE DERIVATIVES AND THEIR USES AS MICROBIOCIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2011-02-24 | — | — | US | disclosed |
| US-20110046088-A1 | IMINIPYRIDINE DERIVATIVES AND THEIR USES AS MICROBIOCIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2011-02-24 | — | — | US | disclosed |
| EP-2125734-A2 | NOVEL MICROBIOCIDES | Syngeta Participations AG (CH) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008101682-A2 | IMINIPYRIDINE DERIVATIVES AND THEIR USES AS MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2008-08-28 | — | — | WO | disclosed |
| WO-2008101682-A2 | IMINIPYRIDINE DERIVATIVES AND THEIR USES AS MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2008-08-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110046088-A1 | IMINIPYRIDINE DERIVATIVES AND THEIR USES AS MICROBIOCIDES | CD14, MYADM, MPO | POLB 769/4885KDM4E 3086/4885KDR 4462/4885 |
| US-20130338105-A1 | IMINIPYRIDINE DERIVATIVES AND THEIR USES AS MICROBIOCIDES | CD14, MYADM, MPO | POLB 842/4885KDM4E 2801/4885KDR 4453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.