Known targets — ChEMBL curated mechanism
POLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PRIM1PRIM2
The experimentally established mechanism targets of Cytidine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.90 |
| ▸ | MTOR | P42345 | 2/20 | 0.90 |
| ▸ | THRB | P10828 | 1/20 | 0.90 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.90 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.90 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.90 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | GMNN | O75496 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.59 |
| ▸ | THPO | P40225 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | HBB | P68871 | 1/20 | 0.59 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.59 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.59 |
| ▸ | NT5E | P21589 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cytidine SCHEMBL376514 | 1.00 | LMNA (0.90) | LMNAMTORTHRBMDM2NCOA1 | |
| Cytarabine SCHEMBL28898416 | 1.00 | LMNA (0.90) | LMNAMTORTHRBMDM2NCOA1 | |
| Cytarabine SCHEMBL458337 | 1.00 | LMNA (0.90) | LMNAMTORTHRBMDM2NCOA1 | |
| Cytarabine SCHEMBL9007590 | 1.00 | LMNA (0.90) | LMNAMTORTHRBMDM2NCOA1 | |
| Cytidine SCHEMBL39902 | 1.00 | LMNA (0.90) | LMNAMTORTHRBMDM2NCOA1 | |
| Cytarabine SCHEMBL285195 | 1.00 | LMNA (0.90) | LMNAMTORTHRBMDM2NCOA1 | |
| Cytidine SCHEMBL104628 | 1.00 | LMNA (0.90) | LMNAMTORTHRBMDM2NCOA1 | |
| Cytidine SCHEMBL6672407 | 0.99 | LMNA (0.88) | LMNAMTORTHRBMDM2NCOA1 | |
| Cytarabine SCHEMBL29084328 | 0.99 | LMNA (0.88) | LMNAMTORTHRBMDM2NCOA1 | |
| Cytidine SCHEMBL2370482 | 0.99 | LMNA (0.88) | LMNAMTORTHRBMDM2NCOA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 537 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116115769-B | Nucleoside phosphate protein intracellular delivery system and preparation method and application thereof | 苏州大学 | 2024-09-06 | — | — | CN | claimed |
| US-11942188-B2 | Obtaining an improved therapeutic ligand | UCB Biopharma SRL (BE) | 2024-03-26 | — | — | US | claimed |
| CN-113784706-B | Multi-layered pharmaceutical or nutraceutical solid dosage forms comprising pyrimidine and/or purine derivatives and B vitamins, their preparation and use | 菲尔若国际公司 | 2024-01-05 | — | — | CN | claimed |
| CN-110730659-B | Compositions for enhancing the efficacy of L-DOPA therapy | N·V·努特里奇亚 | 2023-07-18 | — | — | CN | claimed |
| CN-116370610-A | PH-responsive protein prodrug with similar nucleic acid and preparation method thereof | 苏州大学 | 2023-07-04 | — | — | CN | claimed |
| CN-116115769-A | Nucleoside phosphate protein intracellular delivery system and preparation method and application thereof | 苏州大学 | 2023-05-16 | — | — | CN | claimed |
| CN-113784706-A | Multi-layered pharmaceutical or nutraceutical solid dosage form comprising pyrimidine and/or purine derivatives and B vitamins, preparation and use thereof | 菲尔若国际公司 | 2021-12-10 | — | — | CN | claimed |
| US-20210005277-A1 | Obtaining an Improved Therapeutic Ligand | UCB BIOPHARMA SPRL (BE) | 2021-01-07 | — | — | US | claimed |
| WO-2020082221-A1 | LIVE CELL LIPOSOME OF RHODOTORULA GLUTINIS CARRYING EXOGENOUS POLYPEPTIDE OF RECOMBINANT PHOSPHOCHOLINE CYTIDINE TRANSFERASE AND USE THEREOF | 利时雨 | 2020-04-30 | — | — | WO | claimed |
| CN-105308602-B | The method for the therapeutic ligand that acquisition improves and thus obtained therapeutic ligand | UCB生物制药私人有限公司 | 2019-09-27 | — | — | CN | claimed |
| US-5658734-A | PRODUCING A DETECTABLE BIOPOLYMER BY PHOTOLITHOGRAPHY, DEPROTECTING | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1997-08-19 | — | — | US | claimed |
| EP-0739207-A1 | ENTERAL FORMULA WITH RIBO-NUCLEOTIDES | ABBOTT LABORATORIES (US) | 1996-10-30 | — | — | EP | claimed |
| WO-1995018618-A2 | ENTERAL FORMULA WITH RIBO-NUCLEOTIDES | ABBOTT LAB (US) | 1995-07-13 | — | — | WO | claimed |
| EP-0302807-B1 | Food products enriched with nucleosides and/or nucleotides and preparation thereof | PULEVA UNION IND AGRO GANADERA (ES) | 1994-01-19 | — | — | EP | claimed |
| CN-1059659-A | The diagnosis of viral hepatitis and treatment | HEM RES INC (US) | 1992-03-25 | — | — | CN | claimed |
| CN-1056530-A | Saccharides and synthetic method thereof and equipment | UNIV PENNSYLVANIA (US) | 1991-11-27 | — | — | CN | claimed |
| US-5066500-A | Similar to human milk | UNION INDUSTRIAL Y AGRO-GANADERA, S. A. (UNIASA) (ES) | 1991-11-19 | — | — | US | claimed |
| US-4994442-A | Administering liquid mixtures of nutrients, nucleosides and/or nucleotides | UNION INDUSTRIAL Y AGRO-GANADERA, S.A. (UNIASA) (ES) | 1991-02-19 | — | — | US | claimed |
| EP-0302807-A2 | Food products enriched with nucleosides and/or nucleotides and preparation thereof | PULEVA UNION INDUSTRIAL Y AGRO-GANADERA, S.A. (ES) | 1989-02-08 | — | — | EP | claimed |
| US-4046879-A | TOPICAL | BOEHRINGER INGELHEIM GMBH (DT) | 1977-09-06 | — | — | US | claimed |