Known targets — ChEMBL curated mechanism
POLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PRIM1PRIM2
The experimentally established mechanism targets of Cytidine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.88 |
| ▸ | MTOR | P42345 | 2/20 | 0.88 |
| ▸ | THRB | P10828 | 1/20 | 0.88 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.88 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.88 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.88 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | GMNN | O75496 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.58 |
| ▸ | THPO | P40225 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | HBB | P68871 | 1/20 | 0.58 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cytarabine SCHEMBL458337 | 0.99 | LMNA (0.90) | LMNAMTORTHRBMDM2NCOA1 | |
| Cytarabine SCHEMBL28898416 | 0.99 | LMNA (0.90) | LMNAMTORTHRBMDM2NCOA1 | |
| Cytidine SCHEMBL376514 | 0.99 | LMNA (0.90) | LMNAMTORTHRBMDM2NCOA1 | |
| Cytarabine SCHEMBL9007590 | 0.99 | LMNA (0.90) | LMNAMTORTHRBMDM2NCOA1 | |
| Cytidine SCHEMBL1201153 | 0.99 | LMNA (0.90) | LMNAMTORTHRBMDM2NCOA1 | |
| Cytarabine SCHEMBL285195 | 0.99 | LMNA (0.90) | LMNAMTORTHRBMDM2NCOA1 | |
| Cytidine SCHEMBL104628 | 0.99 | LMNA (0.90) | LMNAMTORTHRBMDM2NCOA1 | |
| Cytidine SCHEMBL39902 | 0.99 | LMNA (0.90) | LMNAMTORTHRBMDM2NCOA1 | |
| Cytidine SCHEMBL6672407 | 0.98 | LMNA (0.88) | LMNAMTORTHRBMDM2NCOA1 | |
| Cytarabine SCHEMBL29084328 | 0.98 | LMNA (0.88) | LMNAMTORTHRBMDM2NCOA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2544553-B2 | CONTROLLING THE TEXTURE OF HIGH-PROTEIN NUTRITIONAL COMPOSITIONS COMPRISING MICELLAR CASEIN | NUTRICIA NV (NL) | 2022-11-09 | — | — | EP | claimed |
| US-10264806-B2 | Controlling the texture of high-protein nutritional compositions comprising micellar casein | N.V. NUTRICIA (NL) | 2019-04-23 | — | — | US | claimed |
| US-9872888-B2 | Use of a nucleotide for improving the heat stability of an aqueous micellar casein composition | N.V. NUTRICIA (NL) | 2018-01-23 | — | — | US | claimed |
| EP-2732710-B1 | Controlling the texture of high-protein nutritional compositions comprising micellar casein | NUTRICIA NV (NL) | 2015-07-29 | — | — | EP | claimed |
| EP-2734060-A1 | USE OF A NUCLEOTIDE FOR IMPROVING THE HEAT STABILITY OF AN AQUEOUS MICELLAR CASEIN COMPOSITION | N.V. Nutricia (NL) | 2014-05-28 | — | — | EP | claimed |
| EP-2732710-A1 | Controlling the texture of high-protein nutritional compositions comprising micellar casein | N.V. Nutricia (NL) | 2014-05-21 | — | — | EP | claimed |
| US-20140135257-A1 | USE OF A NUCLEOTIDE FOR IMPROVING THE HEAT STABILITY OF AN AQUEOUS MICELLAR CASEIN COMPOSITION | N.V. NUTRICIA | 2014-05-15 | — | — | US | claimed |
| EP-2544553-B1 | CONTROLLING THE TEXTURE OF HIGH-PROTEIN NUTRITIONAL COMPOSITIONS COMPRISING MICELLAR CASEIN | NUTRICIA NV (NL) | 2014-02-26 | — | — | EP | claimed |
| US-20130065824-A1 | CONTROLLING THE TEXTURE OF HIGH-PROTEIN NUTRITIONAL COMPOSITIONS COMPRISING MICELLAR CASEIN | N.V. NUTRICIA | 2013-03-14 | — | — | US | claimed |
| WO-2013012324-A1 | USE OF A NUCLEOTIDE FOR IMPROVING THE HEAT STABILITY OF AN AQUEOUS MICELLAR CASEIN COMPOSITION | N.V. NUTRICIA (NL) | 2013-01-24 | — | — | WO | claimed |
| WO-2013012313-A1 | USE OF A NUCLEOTIDE FOR IMPROVING THE HEAT STABILITY OF AN AQUEOUS MICELLAR CASEIN COMPOSITION | N.V. NUTRICIA (NL) | 2013-01-24 | — | — | WO | claimed |
| EP-2544553-A1 | CONTROLLING THE TEXTURE OF HIGH-PROTEIN NUTRITIONAL COMPOSITIONS COMPRISING MICELLAR CASEIN | N.V. Nutricia (NL) | 2013-01-16 | — | — | EP | claimed |
| WO-2011112075-A1 | CONTROLLING THE TEXTURE OF HIGH-PROTEIN NUTRITIONAL COMPOSITIONS COMPRISING MICELLAR CASEIN | N.V. NUTRICIA (NL) | 2011-09-15 | — | — | WO | claimed |
| WO-2011112087-A1 | CONTROLLING THE TEXTURE OF HIGH-PROTEIN NUTRITIONAL COMPOSITIONS COMPRISING MICELLAR CASEIN | N.V. NUTRICIA (NL) | 2011-09-15 | — | — | WO | claimed |
| CN-113784706-B | Multi-layered pharmaceutical or nutraceutical solid dosage forms comprising pyrimidine and/or purine derivatives and B vitamins, their preparation and use | 菲尔若国际公司 | 2024-01-05 | — | — | CN | disclosed |
| US-20240000124-A1 | DAIRY PRODUCT AND PROCESS | FONTERRA COOPERATIVE GROUP LTD (NZ) | 2024-01-04 | — | — | US | disclosed |
| EP-4228417-A1 | DAIRY PRODUCT AND PROCESS | Fonterra Co-Operative Group Limited (NZ) | 2023-08-23 | — | — | EP | disclosed |
| EP-2544553-A1 | CONTROLLING THE TEXTURE OF HIGH-PROTEIN NUTRITIONAL COMPOSITIONS COMPRISING MICELLAR CASEIN | N.V. Nutricia (NL) | 2013-01-16 | — | — | EP | disclosed |
| WO-2011112075-A1 | CONTROLLING THE TEXTURE OF HIGH-PROTEIN NUTRITIONAL COMPOSITIONS COMPRISING MICELLAR CASEIN | N.V. NUTRICIA (NL) | 2011-09-15 | — | — | WO | disclosed |
| WO-2011112087-A1 | CONTROLLING THE TEXTURE OF HIGH-PROTEIN NUTRITIONAL COMPOSITIONS COMPRISING MICELLAR CASEIN | N.V. NUTRICIA (NL) | 2011-09-15 | — | — | WO | disclosed |