Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12013273 | 0.91 | TSHR (0.47) | TSHRKDM4EPOLBCA1ALDH1A1 | |
| SCHEMBL15136628 | 0.87 | CES1 (0.34) | TSHRNAAATDP1L3MBTL1 | |
| SCHEMBL15146256 | 0.87 | CES1 (0.34) | TSHRNAAATDP1L3MBTL1 | |
| SCHEMBL15146261 | 0.85 | CES1 (0.35) | TSHRNAAAKDM4EPOLBPTPN2 | |
| SCHEMBL12013334 | 0.83 | TSHR (0.42) | TSHRKDM4EPOLBCA1ALDH1A1 | |
| SCHEMBL12013282 | 0.82 | SMN1; SMN2 (0.44) | TSHRNAAAKDM4EHTTSMN1; SMN2 | |
| SCHEMBL23227891 | 0.79 | TSHR (0.52) | TSHRNAAAKDM4EPOLBPTPN2 | |
| SCHEMBL5349731 | 0.79 | TSHR (0.52) | TSHRNAAAKDM4EPOLBPTPN2 | |
| SCHEMBL4860052 | 0.79 | TSHR (0.52) | TSHRNAAAKDM4EPOLBPTPN2 | |
| SCHEMBL30124398 | 0.78 | TSHR (0.44) | TSHRNAAAKDM4EPOLBPTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8252778-B2 | Highly fluorinated oils and surfactants and methods of making and using same | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2012-08-28 | — | — | US | disclosed |
| US-20090264397-A1 | HIGHLY FLUORINATED OILS AND SURFACTANTS AND METHODS OF MAKING AND USING SAME | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264397-A1 | HIGHLY FLUORINATED OILS AND SURFACTANTS AND METHODS OF MAKING AND USING SAME | FLOT1, ABCB4, SGMS1 | TSHR 3279/4885NAAA 741/4885KDM4E 4290/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.