SCHEMBL12013652

SCHEMBL12013652

O=C(CCCCCCCCCCCCCC(=O)NCCOCCO)NCCOCCO

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GAA P10253 1/20 0.50
▸ CNR1 P21554 5/20 0.47
▸ CNR2 P34972 3/20 0.47
▸ TSHR P16473 1/20 0.46
▸ NAAA Q02083 1/20 0.44
▸ DNM1 Q05193 1/20 0.43
▸ FAAH O00519 3/20 0.43
▸ SELP P16109 1/20 0.42
▸ HPGD P15428 3/20 0.42
▸ HTT P42858 1/20 0.42
▸ SMN1; SMN2 Q16637 1/20 0.42
▸ ALDH1A1 P00352 2/20 0.41
▸ TRPV1 Q8NER1 1/20 0.41
▸ MEN1 O00255 1/20 0.41
▸ MAPT P10636 1/20 0.41
▸ ALOX12 P18054 1/20 0.41
▸ BLM P54132 1/20 0.41
▸ KMT2A Q03164 1/20 0.41
▸ TDP1 Q9NUW8 1/20 0.41
▸ ENPP2 Q13822 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12013657 1.00 GAA (0.50) GAACNR1CNR2TSHRNAAA
SCHEMBL12013648 1.00 GAA (0.50) GAACNR1CNR2TSHRNAAA
SCHEMBL4263001 1.00 GAA (0.50) GAACNR1CNR2TSHRNAAA
SCHEMBL4270073 1.00 GAA (0.50) GAACNR1CNR2TSHRNAAA
SCHEMBL12752075 0.98 GAA (0.47) GAACNR1CNR2TSHRNAAA
SCHEMBL21554147 0.96 GAA (0.56) GAACNR1CNR2TSHRNAAA
SCHEMBL24983202 0.93 EPHX2 (0.45) GAACNR1CNR2TSHRFAAH
SCHEMBL16182413 0.93 EPHX2 (0.45) GAACNR1CNR2TSHRFAAH
SCHEMBL12857028 0.93 GAA (0.49) GAACNR1CNR2TSHRNAAA
SCHEMBL12944765 0.93 GAA (0.49) GAACNR1CNR2TSHRNAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2151233-B1 TWO-COMPONENT OXIDATIVE HAIR DYE COMPOSITION KAO CORP (JP) 2017-08-09 — — EP disclosed
US-8252272-B2 Hair cosmetic composition KAO CORPORATION (JP) 2012-08-28 — — US disclosed
US-8252272-B2 Hair cosmetic composition KAO CORPORATION (JP) 2012-08-28 — — US disclosed
US-7897143-B2 Amphipathic amide lipid, anionic surfactant, and acid or salt; feel, moisture retention, smoothness, stability; shampoo KAO CORPORATION (JP) 2011-03-01 — — US disclosed
US-7897143-B2 Amphipathic amide lipid, anionic surfactant, and acid or salt; feel, moisture retention, smoothness, stability; shampoo KAO CORPORATION (JP) 2011-03-01 — — US disclosed
US-7892526-B2 Hair cosmetic composition KAO CORPORATION (JP) 2011-02-22 — — US disclosed
US-7892526-B2 Hair cosmetic composition KAO CORPORATION (JP) 2011-02-22 — — US disclosed
EP-2272494-A2 Hair cleansing composition KAO CORPORATION (JP) 2011-01-12 — — EP disclosed
US-7862806-B2 Hair cosmetic composition KAO CORPORATION (JP) 2011-01-04 — — US disclosed
US-7862806-B2 Hair cosmetic composition KAO CORPORATION (JP) 2011-01-04 — — US disclosed
US-20090047231-A1 AQUEOUS HAIR COSMETIC COMPOSITION KAO CORPORATION (JP) 2009-02-19 — — US disclosed
US-20090047231-A1 AQUEOUS HAIR COSMETIC COMPOSITION KAO CORPORATION (JP) 2009-02-19 — — US disclosed
US-20080299063-A1 HAIR COSMETIC COMPOSITION KAO CORPORATION (JP) 2008-12-04 — — US disclosed
US-20080299063-A1 HAIR COSMETIC COMPOSITION KAO CORPORATION (JP) 2008-12-04 — — US disclosed
EP-1468666-B1 Hair shampoo composition KAO CORP (JP) 2008-06-11 — — EP disclosed
US-7351716-B2 Dermatological preparations KAO CORPORATION (JP) 2008-04-01 — — US disclosed
US-7351716-B2 Dermatological preparations KAO CORPORATION (JP) 2008-04-01 — — US disclosed
US-20070166272-A1 HAIR COSMETIC COMPOSITIONS AND PROCESS FOR PRODUCING THE SAME KAO CORPORATION (JP) 2007-07-19 — — US disclosed
US-20070166272-A1 HAIR COSMETIC COMPOSITIONS AND PROCESS FOR PRODUCING THE SAME KAO CORPORATION (JP) 2007-07-19 — — US disclosed
WO-2007064042-A1 AQUEOUS HAIR COSMETIC COMPOSITION KAO CORPORATION (JP) 2007-06-07 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080299063-A1 HAIR COSMETIC COMPOSITION H1-0, H1-3, H1-2 GAA 4375/4885CNR1 741/4885CNR2 749/4885
US-20090047231-A1 AQUEOUS HAIR COSMETIC COMPOSITION POLR1C, CUTA, POLH GAA 4631/4885CNR1 2103/4885CNR2 2425/4885
US-20070166272-A1 HAIR COSMETIC COMPOSITIONS AND PROCESS FOR PRODUCING THE SAME CUTA, SHH, POLR1C GAA 3538/4885CNR1 1886/4885CNR2 2124/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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