SCHEMBL1201416

SCHEMBL1201416

CCN(C)/C=N\c1cc(C#C[Si](C)(C)C)c(Oc2ccc(Cl)c(C(F)(F)F)c2)nc1C

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PLA2G7 Q13093 8/20 0.33
SCN9A Q15858 4/20 0.32
SCN5A Q14524 1/20 0.32
SLC6A4 P31645 1/20 0.30
HRH3 Q9Y5N1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12878798 1.00 PLA2G7 (0.33) PLA2G7SCN9ASCN5ASLC6A4HRH3
SCHEMBL1201417 1.00 PLA2G7 (0.33) PLA2G7SCN9ASCN5ASLC6A4HRH3
SCHEMBL12878958 0.90 PLA2G7 (0.38) PLA2G7
SCHEMBL17974610 0.88 PLA2G7 (0.32) PLA2G7SCN9ASCN5A
SCHEMBL1201814 0.85 PLA2G7 (0.35) PLA2G7SCN9ASCN5A
SCHEMBL1201812 0.85 PLA2G7 (0.35) PLA2G7SCN9ASCN5A
SCHEMBL12878793 0.85 PLA2G7 (0.35) PLA2G7SCN9ASCN5A
SCHEMBL1201885 0.81 PLA2G7 (0.34) PLA2G7SCN9ASCN5A
SCHEMBL12878790 0.81 PLA2G7 (0.34) PLA2G7SCN9ASCN5A
SCHEMBL1201884 0.81 PLA2G7 (0.34) PLA2G7SCN9ASCN5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9096525-B2 Iminipyridine derivatives and their uses as microbiocides SYNGENTA CROP PROTECTION, LLC (US) 2015-08-04 US disclosed
US-20130338105-A1 IMINIPYRIDINE DERIVATIVES AND THEIR USES AS MICROBIOCIDES SYNGENTA CROP PROTECTION LLC (US) 2013-12-19 US disclosed
US-8513286-B2 Iminipyridine derivatives and their uses as microbiocides SYNGENTA CROP PROTECTION LLC (US) 2013-08-20 US disclosed
US-20110046088-A1 IMINIPYRIDINE DERIVATIVES AND THEIR USES AS MICROBIOCIDES SYNGENTA CROP PROTECTION, INC. (US) 2011-02-24 US disclosed
EP-2125734-A2 NOVEL MICROBIOCIDES Syngeta Participations AG (CH) 2009-12-02 EP disclosed
WO-2008101682-A2 IMINIPYRIDINE DERIVATIVES AND THEIR USES AS MICROBIOCIDES SYNGENTA PARTICIPATIONS AG (CH) 2008-08-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110046088-A1 IMINIPYRIDINE DERIVATIVES AND THEIR USES AS MICROBIOCIDES CD14, MYADM, MPO PLA2G7 1795/4885SCN9A 2067/4885SCN5A 2584/4885
US-20130338105-A1 IMINIPYRIDINE DERIVATIVES AND THEIR USES AS MICROBIOCIDES CD14, MYADM, MPO PLA2G7 1755/4885SCN9A 2250/4885SCN5A 2544/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.