SCHEMBL12015063

SCHEMBL12015063

COC(=O)C1(O)C[C@@H](O)[C@@H](C)C([C@H](O)[C@H](O)CO)O1

nearest known ligand 0.54

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 1/20 0.54
▸ NANP Q8TBE9 3/20 0.39
▸ NEU1 Q99519 5/20 0.32
▸ NEU3 Q9UQ49 5/20 0.32
▸ NEU2 Q9Y3R4 5/20 0.32
▸ NEU4 Q8WWR8 5/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15471527 1.00 L3MBTL1 (0.54) L3MBTL1NANPNEU1NEU3NEU2
SCHEMBL12731860 1.00 L3MBTL1 (0.54) L3MBTL1NANPNEU1NEU3NEU2
SCHEMBL12302605 1.00 L3MBTL1 (0.54) L3MBTL1NANPNEU1NEU3NEU2
SCHEMBL16272856 1.00 L3MBTL1 (0.54) L3MBTL1NANPNEU1NEU3NEU2
SCHEMBL14648888 1.00 L3MBTL1 (0.54) L3MBTL1NANPNEU1NEU3NEU2
SCHEMBL10077901 0.90 L3MBTL1 (0.43) L3MBTL1NANP
SCHEMBL8905452 0.88 L3MBTL1 (0.55) L3MBTL1NANPNEU1NEU3NEU2
SCHEMBL15143127 0.88 L3MBTL1 (0.44) L3MBTL1NANP
SCHEMBL15806332 0.86 L3MBTL1 (0.53) L3MBTL1NANPNEU1NEU3NEU2
SCHEMBL17936315 0.86 L3MBTL1 (0.53) L3MBTL1NANPNEU1NEU3NEU2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170007712-A1 GLYCOPEGYLATION METHODS AND PROTEINS/PEPTIDES PRODUCED BY THE METHODS NOVO NORDISK A/S (DK) 2017-01-12 — — US disclosed
US-20160200795-A1 FACTOR VIII: REMODELING AND GLYCOCONJUGATION OF FACTOR VIII NOVO NORDISK A/S (DK) 2016-07-14 — — US disclosed
US-20160193353-A1 FACTOR VIII: REMODELING AND GLYCOCONJUGATION OF FACTOR VIII NOVO NORDISK A/S (DK) 2016-07-07 — — US disclosed
US-9237764-B2 Production of 6′-O-sialyllactose and intermediates GLYCOM A/S (DK) 2016-01-19 — — US disclosed
US-20150343080-A1 GLYCOPEGYLATION METHODS AND PROTEINS/PEPTIDES PRODUCED BY THE METHODS NOVO NORDISK AS (DK) 2015-12-03 — — US disclosed
US-8853161-B2 Glycopegylation methods and proteins/peptides produced by the methods NOVO NORDISK A/S (DK) 2014-10-07 — — US disclosed
US-20140294762-A1 GLYCOPEGYLATION METHODS AND PROTEINS/PEPTIDES PRODUCED BY THE METHODS NOVO NORDISK A/S (DK) 2014-10-02 — — US disclosed
US-20140170728-A1 Factor IX: Remodeling and Glycoconjugation of Factor IX NOVO NORDISK A/S (DK) 2014-06-19 — — US disclosed
US-20130035481-A1 PRODUCTION OF 6'-O-SIALYLLACTOSE AND INTERMEDIATES GLYCOM A/S (DK) 2013-02-07 — — US disclosed
US-20120220517-A1 Glycopegylation Methods and Proteins/Peptides Produced by the Methods NOVO NORDISK A/S (DK) 2012-08-30 — — US disclosed
US-20100015684-A1 FACTOR VII: REMODELING AND GLYCOCONJUGATION OF FACTOR VII NEOSE TECHNOLOGIES, INC. 2010-01-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160200795-A1 FACTOR VIII: REMODELING AND GLYCOCONJUGATION OF FACTOR VIII F13B, F8, F13A1 L3MBTL1 3461/4885NANP 473/4885NEU1 217/4885
US-20120220517-A1 Glycopegylation Methods and Proteins/Peptides Produced by the Methods PTMS, ANPEP, NGLY1 L3MBTL1 1974/4885NANP 341/4885NEU1 88/4885
US-20160193353-A1 FACTOR VIII: REMODELING AND GLYCOCONJUGATION OF FACTOR VIII F13B, F8, F13A1 L3MBTL1 3461/4885NANP 473/4885NEU1 217/4885
US-20100015684-A1 FACTOR VII: REMODELING AND GLYCOCONJUGATION OF FACTOR VII F13B, F7, HABP2 L3MBTL1 2634/4885NANP 656/4885NEU1 187/4885
US-20170007712-A1 GLYCOPEGYLATION METHODS AND PROTEINS/PEPTIDES PRODUCED BY THE METHODS PTMS, ANPEP, NGLY1 L3MBTL1 1974/4885NANP 341/4885NEU1 88/4885
US-20130035481-A1 PRODUCTION OF 6'-O-SIALYLLACTOSE AND INTERMEDIATES ST6GAL1, FUT6, FUT5 L3MBTL1 4417/4885NANP 76/4885NEU1 14/4885
US-20150343080-A1 GLYCOPEGYLATION METHODS AND PROTEINS/PEPTIDES PRODUCED BY THE METHODS PTMS, ANPEP, NGLY1 L3MBTL1 1974/4885NANP 341/4885NEU1 88/4885
US-20140294762-A1 GLYCOPEGYLATION METHODS AND PROTEINS/PEPTIDES PRODUCED BY THE METHODS PTMS, ANPEP, NGLY1 L3MBTL1 1974/4885NANP 341/4885NEU1 88/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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