Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.60 |
| ▸ | TGM2 | P21980 | 1/20 | 0.58 |
| ▸ | HINT1 | P49773 | 4/20 | 0.58 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.56 |
| ▸ | KRAS | P01116 | 8/20 | 0.53 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.53 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.53 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.51 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.51 |
| ▸ | GSK3A | P49840 | 2/20 | 0.51 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.51 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12646612 | 1.00 | NT5E (0.60) | NT5ETGM2HINT1FUT5KRAS | |
| SCHEMBL12590132 | 1.00 | NT5E (0.60) | NT5ETGM2HINT1FUT5KRAS | |
| SCHEMBL18058962 | 0.93 | NT5E (0.58) | NT5ETGM2HINT1FUT5KRAS | |
| SCHEMBL20762956 | 0.91 | TGM2 (0.65) | NT5ETGM2HINT1FUT5KRAS | |
| SCHEMBL12590073 | 0.91 | NT5E (0.53) | NT5ETGM2HINT1FUT5KRAS | |
| SCHEMBL33190 | 0.91 | NT5E (0.53) | NT5ETGM2HINT1FUT5KRAS | |
| SCHEMBL12015141 | 0.91 | NT5E (0.53) | NT5ETGM2HINT1FUT5KRAS | |
| SCHEMBL12590130 | 0.90 | HINT1 (0.57) | NT5ETGM2HINT1FUT5KRAS | |
| SCHEMBL12015199 | 0.90 | HINT1 (0.57) | NT5ETGM2HINT1FUT5KRAS | |
| SCHEMBL12087514 | 0.90 | HINT1 (0.57) | NT5ETGM2HINT1FUT5KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120220649-A1 | MODIFIED DOUBLE-STRANDED POLYNUCLEOTIDE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120220649-A1 | MODIFIED DOUBLE-STRANDED POLYNUCLEOTIDE | POLM, POLN, PNKP | NT5E 104/4885TGM2 3429/4885HINT1 2414/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.