Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.65 |
| ▸ | NT5E | P21589 | 1/20 | 0.65 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.63 |
| ▸ | KRAS | P01116 | 8/20 | 0.59 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.58 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.58 |
| ▸ | HINT1 | P49773 | 1/20 | 0.56 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.55 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.55 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.55 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.55 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.54 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.54 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.54 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25070726 | 0.94 | TGM2 (0.66) | TGM2NT5EFUT5KRASIMPDH2 | |
| SCHEMBL25552773 | 0.92 | TGM2 (0.60) | TGM2NT5EFUT5KRASIMPDH2 | |
| SCHEMBL12015188 | 0.91 | NT5E (0.60) | TGM2NT5EFUT5KRASIMPDH2 | |
| SCHEMBL12590132 | 0.91 | NT5E (0.60) | TGM2NT5EFUT5KRASIMPDH2 | |
| SCHEMBL12646612 | 0.91 | NT5E (0.60) | TGM2NT5EFUT5KRASIMPDH2 | |
| SCHEMBL18258303 | 0.91 | NT5E (0.77) | TGM2NT5EFUT5KRASIMPDH2 | |
| SCHEMBL14659957 | 0.91 | NT5E (0.77) | TGM2NT5EFUT5KRASIMPDH2 | |
| SCHEMBL29160869 | 0.91 | NT5E (0.77) | TGM2NT5EFUT5KRASIMPDH2 | |
| SCHEMBL27378469 | 0.91 | RNASEL (0.67) | TGM2NT5ERNASELP2RY2P2RX3 | |
| SCHEMBL20763046 | 0.90 | FUT5 (0.57) | TGM2NT5EFUT5KRASIMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019034866-A1 | BICYCLIC PEPTIDE LIGAND STING CONJUGATES AND USES THEREOF | Bicyclerd Limited (GB) | 2019-02-21 | — | — | WO | disclosed |