Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | SENP2 | Q9HC62 | 3/20 | 0.42 |
| ▸ | SENP1 | Q9P0U3 | 3/20 | 0.42 |
| ▸ | SUMO2 | P61956 | 2/20 | 0.42 |
| ▸ | SUMO1 | P63165 | 2/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.42 |
| ▸ | PHLPP2 | Q6ZVD8 | 3/20 | 0.41 |
| ▸ | APP | P05067 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.41 |
| ▸ | SLC7A11 | Q9UPY5 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15044929 | 0.90 | SENP2 (0.44) | THRBSENP2SENP1SUMO2SUMO1 | |
| SCHEMBL15044928 | 0.90 | SENP2 (0.44) | THRBSENP2SENP1SUMO2SUMO1 | |
| SCHEMBL13604262 | 0.89 | THRB (0.51) | THRBSENP2SENP1SUMO2SUMO1 | |
| SCHEMBL13792698 | 0.89 | THRB (0.51) | THRBSENP2SENP1SUMO2SUMO1 | |
| SCHEMBL15044925 | 0.85 | SENP2 (0.53) | THRBSENP2SENP1SUMO2SUMO1 | |
| SCHEMBL14537251 | 0.85 | PHLPP2 (0.41) | THRBSENP2SENP1SUMO2SUMO1 | |
| SCHEMBL13793489 | 0.84 | THRB (0.47) | THRBSENP2SENP1SUMO2SUMO1 | |
| SCHEMBL13880627 | 0.84 | ENPP2 (0.52) | THRBSENP2SENP1SUMO2SUMO1 | |
| SCHEMBL13880565 | 0.84 | THRB (0.62) | THRBSENP2SUMO2SUMO1SENP7 | |
| SCHEMBL12053411 | 0.81 | THRB (0.43) | THRBSENP2SENP1SUMO2SUMO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8349029-B2 | Fiber-reactive azo dyes and dye mixtures, preparation thereof and use thereof | DYSTAR COLOURS DEUTSCHLAND GMBH (DE) | 2013-01-08 | — | — | US | disclosed |
| US-20120216356-A1 | FIBER-REACTIVE AZO DYES AND DYE MIXTURES, PREPARATION THEREOF AND USE THEREOF | DYSTAR COLOURS DEUTSCHLAND GMBH (DE) | 2012-08-30 | — | — | US | disclosed |