Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14302947 | 0.84 | CYP3A4 (0.36) | TSHRCYP3A4THRBALDH1A1HSD17B10 | |
| SCHEMBL12018014 | 0.84 | SCN1A (0.45) | TSHRCYP3A4THRBKMT2ASMN1; SMN2 | |
| SCHEMBL12018015 | 0.82 | ADRB2 (0.43) | NPC1HPGDKMT2AALDH1A1GAA | |
| SCHEMBL12019253 | 0.81 | TSHR (0.40) | RAB9ANPC1TSHRHTTHPGD | |
| SCHEMBL13497084 | 0.79 | ALDH1A1 (0.45) | TSHRHPGDCYP3A4THRBKMT2A | |
| SCHEMBL11205065 | 0.76 | ALDH1A1 (0.44) | TSHRHPGDCYP3A4THRBKMT2A | |
| SCHEMBL3155745 | 0.76 | ALDH1A1 (0.44) | TSHRHPGDCYP3A4THRBKMT2A | |
| SCHEMBL10168250 | 0.74 | ALDH1A1 (0.45) | TSHRHPGDCYP3A4THRBALDH1A1 | |
| SCHEMBL7925089 | 0.74 | TSHR (0.50) | TSHRCYP3A4ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL707088 | 0.74 | TSHR (0.53) | TSHRCYP3A4ALDH1A1SMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2496549-B1 | NEW, NON-CRYSTALLISING METHACRYLATE, ITS MANUFACTURE AND APPLICATION | BAYER IP GMBH (DE) | 2014-10-08 | — | — | EP | disclosed |
| EP-2496549-B1 | NEW, NON-CRYSTALLISING METHACRYLATE, ITS MANUFACTURE AND APPLICATION | BAYER IP GMBH (DE) | 2014-10-08 | — | — | EP | disclosed |
| US-20120219885-A1 | NOVEL NON-CRYSTALLIZING METHACRYLATES, PRODUCTION AND USE THEREOF | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2012-08-30 | — | — | US | disclosed |
| US-20120219885-A1 | NOVEL NON-CRYSTALLIZING METHACRYLATES, PRODUCTION AND USE THEREOF | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2012-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120219885-A1 | NOVEL NON-CRYSTALLIZING METHACRYLATES, PRODUCTION AND USE THEREOF | MEP1A, MMAB, RHOA | RAB9A 2969/4885NPC1 4492/4885TSHR 4836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.