Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12018204 | 0.89 | BCHE (0.50) | BCHEKDM4ESIGMAR1KCNH2CHRM2 | |
| SCHEMBL27890795 | 0.81 | BCHE (0.61) | BCHEKDM4ESIGMAR1KCNH2CHRM2 | |
| SCHEMBL148130 | 0.72 | TP53 (0.44) | SIGMAR1 | |
| SCHEMBL11132326 | 0.72 | KCNH2 (0.52) | BCHESIGMAR1KCNH2CHRM2HTR1A | |
| SCHEMBL6229666 | 0.70 | CA1 (0.42) | KDM4ESIGMAR1 | |
| SCHEMBL4871162 | 0.69 | IDO1 (0.55) | KCNH2CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL6568305 | 0.69 | KCNH2 (0.45) | BCHEKCNH2CHRM2HTR1AADRA2A | |
| SCHEMBL4545011 | 0.69 | ACHE (0.40) | BCHEKDM4ESIGMAR1 | |
| SCHEMBL12861055 | 0.69 | HSD17B10 (0.38) | — | |
| SCHEMBL24486783 | 0.68 | CHRM2 (0.56) | KDM4ESIGMAR1KCNH2CHRM2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120216867-A1 | FULLERENE DERIVATIVES | NATIONAL UNIVERSITY CORPORATION TOTTORI UNIVERSITY (JP) | 2012-08-30 | — | — | US | disclosed |