Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 3/20 | 0.44 |
| ▸ | ECE1 | P42892 | 3/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | GNPAT | O15228 | 1/20 | 0.33 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.32 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | TASP1 | Q9H6P5 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13412762 | 0.87 | BMP1 (0.41) | BMP1ECE1DPP4DPP8DPP9 | |
| SCHEMBL14553976 | 0.84 | BMP1 (0.51) | BMP1DPP4DPP8DPP9GNPAT | |
| SCHEMBL12930062 | 0.82 | KMT2A (0.40) | BMP1DPP4DPP8DPP9KMT2A | |
| SCHEMBL13233708 | 0.82 | KMT2A (0.40) | BMP1DPP4DPP8DPP9KMT2A | |
| SCHEMBL16656707 | 0.82 | KMT2A (0.40) | BMP1DPP4DPP8DPP9KMT2A | |
| SCHEMBL14553986 | 0.82 | BMP1 (0.40) | BMP1DPP4DPP8DPP9GNPAT | |
| SCHEMBL12998157 | 0.82 | ECE1 (0.37) | BMP1ECE1GNPATSIRT5TASP1 | |
| SCHEMBL13930091 | 0.81 | ECE1 (0.47) | BMP1ECE1DPP4DPP8DPP9 | |
| SCHEMBL17521529 | 0.80 | BMP1 (0.39) | BMP1ECE1DPP4DPP8DPP9 | |
| SCHEMBL14417629 | 0.80 | ECE1 (0.42) | BMP1ECE1GNPATMMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120220522-A1 | ESTER INSULIN | KENT STEPHEN B H (US) | 2012-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120220522-A1 | ESTER INSULIN | IAPP, IGFBP4, INSR | BMP1 3172/4885ECE1 432/4885DPP4 23/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.