Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.36 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12018762 | 1.00 | HTT (0.43) | HTTSMN1; SMN2FFAR4GSTP1LTA4H | |
| SCHEMBL12018759 | 0.83 | ACHE (0.48) | SMN1; SMN2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL12018760 | 0.83 | ACHE (0.48) | SMN1; SMN2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL24322042 | 0.79 | HTT (0.62) | HTTSMN1; SMN2FFAR4GSTP1LTA4H | |
| SCHEMBL20419433 | 0.79 | HTT (0.62) | HTTSMN1; SMN2FFAR4GSTP1LTA4H | |
| SCHEMBL822790 | 0.79 | HTT (0.62) | HTTSMN1; SMN2FFAR4GSTP1LTA4H | |
| SCHEMBL24871259 | 0.76 | HTT (0.50) | HTTSMN1; SMN2FFAR4GSTP1LTA4H | |
| SCHEMBL537243 | 0.75 | HTT (0.57) | HTTSMN1; SMN2FFAR4GSTP1LTA4H | |
| SCHEMBL2058591 | 0.75 | HTT (0.57) | HTTSMN1; SMN2FFAR4GSTP1LTA4H | |
| Diphenylether SCHEMBL9751563 | 0.75 | LTA4H (0.57) | HTTSMN1; SMN2FFAR4GSTP1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120217445-A1 | POLYMER COMPOUND AND METHOD FOR PRODUCING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120217445-A1 | POLYMER COMPOUND AND METHOD FOR PRODUCING THE SAME | PUF60, PARG, PCBP1 | HTT 2734/4885SMN1; SMN2 1707/4885FFAR4 4270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.