SCHEMBL537243

SCHEMBL537243

Cc1ccc(Oc2ccc(-c3ccccc3)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 3/20 0.57
SMN1; SMN2 Q16637 3/20 0.57
TEAD4 Q15561 1/20 0.54
ALDH1A1 P00352 2/20 0.52
MAPT P10636 2/20 0.52
POLB P06746 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
NPSR1 Q6W5P4 2/20 0.51
LMNA P02545 2/20 0.51
LTA4H P09960 4/20 0.50
TSHR P16473 2/20 0.50
FFAR4 Q5NUL3 1/20 0.49
FFAR1 O14842 1/20 0.47
GSTP1 P09211 1/20 0.47
NPC1 O15118 1/20 0.47
HPGD P15428 1/20 0.47
NFKB1 P19838 1/20 0.47
RAB9A P51151 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2058591 1.00 HTT (0.57) HTTSMN1; SMN2TEAD4ALDH1A1MAPT
SCHEMBL16361074 1.00 HTT (0.57) HTTSMN1; SMN2TEAD4ALDH1A1MAPT
Biphenyl SCHEMBL312988 0.98 HTT (0.59) HTTSMN1; SMN2TEAD4ALDH1A1MAPT
SCHEMBL20419433 0.95 HTT (0.62) HTTSMN1; SMN2TEAD4ALDH1A1MAPT
Diphenylether SCHEMBL9751563 0.95 LTA4H (0.57) HTTSMN1; SMN2TEAD4ALDH1A1MAPT
SCHEMBL24322042 0.95 HTT (0.62) HTTSMN1; SMN2TEAD4ALDH1A1MAPT
SCHEMBL822790 0.95 HTT (0.62) HTTSMN1; SMN2TEAD4ALDH1A1MAPT
SCHEMBL5872093 0.90 TEAD4 (0.64) HTTSMN1; SMN2TEAD4ALDH1A1MAPT
SCHEMBL1688850 0.90 TEAD4 (0.64) HTTSMN1; SMN2TEAD4ALDH1A1MAPT
SCHEMBL12336216 0.90 TEAD4 (0.64) HTTSMN1; SMN2TEAD4ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 253 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9517651-B2 Developer for thermal recording media and thermal composition media using the same PERFORMANCE CHEMICALS, INC. (US) 2016-12-13 US claimed
US-20160089919-A1 NOVEL DEVELOPER FOR THERMAL RECORDING MEDIA AND THERMAL COMPOSITION MEDIA USING THE SAME MARUBENI AMERICA CORPORATION 2016-03-31 US claimed
US-7071144-B2 Heat response; confining images; reducing residues on print head; colorless dyes and developer; mixture of diphenyl sulfone compound, amide and fluoran dye MITSUBISHI PAPER MILLS, LTD. (JP) 2006-07-04 US claimed
US-20050030366-A1 Thermal recording material MITSUBISHI PAPER MILLS LTD. (JP) 2005-02-10 US claimed
EP-0675002-B1 Heat-sensitive recording material FUJI PHOTO FILM CO LTD (JP) 1998-02-25 EP claimed
EP-0506967-B1 THERMAL RECORDING MEDIUM NEW OJI PAPER CO LTD (JP) 1996-11-13 EP claimed
EP-0599580-B1 Thermal recording sheet JUJO PAPER CO LTD (JP) 1996-02-07 EP claimed
US-5446009-A Thermal color developing layer consists of an organic color developer, a higher fatty acid metal double salt and an electron doner; storage stability, oil/plasticizing/weather/ light resistance NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1995-08-29 US claimed
EP-0599580-A1 Thermal recording sheet NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1994-06-01 EP claimed
EP-0422680-B1 Heat-sensitive recording sheet JUJO PAPER CO LTD (JP) 1994-06-01 EP claimed
US-5296440-A Having recording layer containing alkaline pigment and 2,2*-methylenebis(4,6-di-tert-butylphenyl)phosphate or salts KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1994-03-22 US claimed
EP-0506967-A1 THERMAL RECORDING MEDIUM NEW OJI PAPER CO., LTD. (JP) 1992-10-07 EP claimed
US-5118656-A Color developing layer of basic chromogenic dye and color developing agent hydoxy-propoxy diphenyl sulfone and phenolic substance; quality JUJO PAPER CO., LTD. (JP) 1992-06-02 US claimed
US-4982010-A Method of producing 4-biphenyl p-tolyl ether YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1991-01-01 US claimed
JP-5016531-A None JP disclosed
JP-7017890-A None JP disclosed
JP-7017890-A None JP disclosed
US-4229564-A SUITABLE FOR MELT PROCESSING AND EXTRUSION COATINGS RAYCHEM CORPORATION (US) 1980-10-21 US disclosed
US-4111908-A POLYKETONES AND METHODS THEREFOR RAYCHEM CORPORATION (US) 1978-09-05 US disclosed
US-3965146-A POLYMER INTERMEDIATE RAYCHEM CORPORATION (US) 1976-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160089919-A1 NOVEL DEVELOPER FOR THERMAL RECORDING MEDIA AND THERMAL COMPOSITION MEDIA USING THE SAME HPD, PNMT, HTR3C HTT 576/4885SMN1; SMN2 3135/4885TEAD4 1482/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.