Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | GPR183 | P32249 | 1/20 | 0.43 |
| ▸ | APLNR | P35414 | 1/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.43 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.41 |
| ▸ | POLQ | O75417 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 2/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27637724 | 0.85 | NPC1 (0.51) | MAPTNPC1POLBDGAT2POLQ | |
| SCHEMBL3832537 | 0.84 | ALDH1A1 (0.45) | MAPTNPC1POLBADRB2S1PR1 | |
| SCHEMBL1203021 | 0.84 | NPC1 (0.48) | MAPTNPC1POLBDGAT2POLQ | |
| SCHEMBL3827436 | 0.84 | DGAT2 (0.47) | MAPTNPC1POLBADRB2S1PR1 | |
| SCHEMBL3830616 | 0.83 | NPC1 (0.47) | MAPTNPC1POLBDGAT2POLQ | |
| SCHEMBL3826432 | 0.83 | NPC1 (0.46) | MAPTNPC1POLBADRB2S1PR1 | |
| SCHEMBL1203559 | 0.83 | NPC1 (0.55) | NPC1POLBPDE4APDE4BPDE4C | |
| SCHEMBL1202926 | 0.82 | NPC1 (0.46) | MAPTNPC1POLBDGAT2POLQ | |
| SCHEMBL1201954 | 0.82 | NPC1 (0.48) | MAPTNPC1POLBDGAT2POLQ | |
| SCHEMBL27637717 | 0.82 | NPC1 (0.48) | MAPTNPC1POLBDGAT2POLQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110028521-A1 | PESTICIDAL COMPOSITION, AND METHOD FOR CONTROLLING PESTS | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2011-02-03 | — | — | US | claimed |
| EP-2263455-A1 | HARMFUL ORGANISM CONTROL COMPOSITION, AND METHOD FOR CONTROL OF HARMFUL ORGANISMS | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2010-12-22 | — | — | EP | claimed |
| EP-1460071-B1 | N-HETEROARYLNICOTINAMIDE DERIVATIVES | MITSUI CHEMICALS AGRO INC (JP) | 2009-09-16 | — | — | EP | claimed |
| US-7015236-B2 | N-heteroarylnicotinamide derivatives | SANKYO AGRO COMPANY, LIMITED (JP) | 2006-03-21 | — | — | US | claimed |
| US-20050004368-A1 | N-heteroarylnicotinamide derivatives | SANKYO ARGO COMPANY LIMITED (JP) | 2005-01-06 | — | — | US | claimed |
| EP-1460071-A1 | N-HETEROARYLNICOTINAMIDE DERIVATIVES | Sankyo Agro Company, Limited (JP) | 2004-09-22 | — | — | EP | claimed |
| US-9848601-B2 | Pesticidal composition, and method for controlling pests | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2017-12-26 | — | — | US | disclosed |
| EP-2263455-B1 | HARMFUL ORGANISM CONTROL COMPOSITION, AND METHOD FOR CONTROL OF HARMFUL ORGANISMS | ISHIHARA SANGYO KAISHA (JP) | 2016-03-16 | — | — | EP | disclosed |
| US-20110028521-A1 | PESTICIDAL COMPOSITION, AND METHOD FOR CONTROLLING PESTS | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2011-02-03 | — | — | US | disclosed |
| EP-2263455-A1 | HARMFUL ORGANISM CONTROL COMPOSITION, AND METHOD FOR CONTROL OF HARMFUL ORGANISMS | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2010-12-22 | — | — | EP | disclosed |
| EP-1460071-B1 | N-HETEROARYLNICOTINAMIDE DERIVATIVES | MITSUI CHEMICALS AGRO INC (JP) | 2009-09-16 | — | — | EP | disclosed |
| US-7015236-B2 | N-heteroarylnicotinamide derivatives | SANKYO AGRO COMPANY, LIMITED (JP) | 2006-03-21 | — | — | US | disclosed |
| US-20050004368-A1 | N-heteroarylnicotinamide derivatives | SANKYO ARGO COMPANY LIMITED (JP) | 2005-01-06 | — | — | US | disclosed |
| EP-1460071-A1 | N-HETEROARYLNICOTINAMIDE DERIVATIVES | Sankyo Agro Company, Limited (JP) | 2004-09-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110028521-A1 | PESTICIDAL COMPOSITION, AND METHOD FOR CONTROLLING PESTS | CHRM2, CHRM1, PHOSPHO1 | MAPT 4690/4885NPC1 2146/4885POLB 4441/4885 |
| US-20050004368-A1 | N-heteroarylnicotinamide derivatives | CBR3, CBR1, NAT1 | MAPT 4033/4885NPC1 673/4885POLB 3500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.