Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 2/20 | 0.45 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.45 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.40 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.33 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.33 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7249032 | 0.86 | GRM4 (0.57) | CDK2DYRK1BGRM4DYRK1AKDM4E | |
| SCHEMBL12019060 | 0.84 | GRM4 (0.39) | CDK2DYRK1BGRM4CYP2A6CYP2E1 | |
| SCHEMBL12019068 | 0.79 | MAP3K5 (0.39) | GRM4CYP2A6CYP2E1TLR8TGFBR1 | |
| SCHEMBL12019075 | 0.78 | GRM4 (0.47) | GRM4CYP2A6CYP2E1CYP3A4TLR8 | |
| SCHEMBL12019059 | 0.78 | MAT2A (0.41) | GRM4TLR8TGFBR1 | |
| SCHEMBL12019071 | 0.77 | GAA (0.48) | GRM4CYP2A6CYP2E1CYP3A4TLR8 | |
| SCHEMBL12019070 | 0.77 | GRM4 (0.39) | GRM4CYP2A6CYP2E1CYP3A4TLR8 | |
| SCHEMBL12019076 | 0.76 | CYP2A6 (0.43) | GRM4DYRK1ACYP2A6CYP2E1CYP3A4 | |
| SCHEMBL17477104 | 0.76 | GAA (0.50) | GRM4CYP2A6CYP2E1CYP3A4TLR8 | |
| SCHEMBL12019073 | 0.76 | CYP2A6 (0.46) | GRM4CYP2A6CYP2E1CYP3A4TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120220453-A1 | PESTICIDAL COMPOSTIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2012-08-30 | — | — | US | disclosed |
| US-20120220453-A1 | PESTICIDAL COMPOSTIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2012-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120220453-A1 | PESTICIDAL COMPOSTIONS AND PROCESSES RELATED THERETO | DDT, ACHE, NOTUM | CDK2 3687/4885DYRK1B 3983/4885GRM4 3600/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.