Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | IDH1 | O75874 | 2/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 9/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | IDH2 | P48735 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12004864 | 0.84 | SLC6A9 (0.36) | MAT2APTGS2IDH1TGFBR1GABRA1 | |
| SCHEMBL12019060 | 0.82 | GRM4 (0.39) | MAT2APTGS2IDH1TGFBR1TLR8 | |
| SCHEMBL12019064 | 0.81 | PTGS2 (0.36) | MAT2APTGS2TGFBR1TLR8GRM4 | |
| SCHEMBL12019067 | 0.80 | PTGS2 (0.36) | MAT2APTGS2TLR8GRM4 | |
| SCHEMBL12019068 | 0.80 | MAP3K5 (0.39) | TGFBR1TLR8GRM4 | |
| SCHEMBL12019069 | 0.79 | DGAT1 (0.38) | PTGS2TGFBR1TLR8GRM4 | |
| SCHEMBL12019078 | 0.79 | PTGS2 (0.42) | MAT2APTGS2TLR8GRM4 | |
| SCHEMBL12019070 | 0.78 | GRM4 (0.39) | PTGS2TLR8GRM4 | |
| SCHEMBL12019062 | 0.78 | CDK2 (0.45) | TGFBR1TLR8GRM4 | |
| SCHEMBL2183687 | 0.77 | IDH1 (0.41) | MAT2APTGS2IDH1TGFBR1GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120220453-A1 | PESTICIDAL COMPOSTIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2012-08-30 | — | — | US | disclosed |
| US-20120220453-A1 | PESTICIDAL COMPOSTIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2012-08-30 | — | — | US | disclosed |
| WO-2012116246-A2 | PESTICIDAL COMPOSTIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2012-08-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120220453-A1 | PESTICIDAL COMPOSTIONS AND PROCESSES RELATED THERETO | DDT, ACHE, NOTUM | MAT2A 716/4885PTGS2 686/4885IDH1 1225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.