Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 19/20 | 0.73 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.58 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.58 |
| ▸ | DRD2 | P14416 | 1/20 | 0.58 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.58 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.58 |
| ▸ | CNR1 | P21554 | 1/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.58 |
| ▸ | HTR2A | P28223 | 1/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.58 |
| ▸ | MC4R | P32245 | 1/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.58 |
| ▸ | HRH1 | P35367 | 1/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.58 |
| ▸ | DRD3 | P35462 | 1/20 | 0.58 |
| ▸ | SCN1A | P35498 | 1/20 | 0.58 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2778709 | 1.00 | SIGMAR1 (0.73) | SIGMAR1ADRB2ADRB1HTR1AADORA3 | |
| SCHEMBL9175505 | 1.00 | SIGMAR1 (0.73) | SIGMAR1ADRB2ADRB1HTR1AADORA3 | |
| SCHEMBL9191015 | 0.95 | SIGMAR1 (0.72) | SIGMAR1ADRB2ADRB1HTR1AADORA3 | |
| SCHEMBL30384619 | 0.91 | SIGMAR1 (0.86) | SIGMAR1ADRB2ADRB1HTR1AADORA3 | |
| SCHEMBL20689723 | 0.89 | SIGMAR1 (0.86) | SIGMAR1ADRB2ADRB1HTR1AADORA3 | |
| SCHEMBL20689707 | 0.89 | SIGMAR1 (0.86) | SIGMAR1ADRB2ADRB1HTR1AADORA3 | |
| SCHEMBL20689714 | 0.89 | SIGMAR1 (0.86) | SIGMAR1ADRB2ADRB1HTR1AADORA3 | |
| SCHEMBL5577576 | 0.87 | SIGMAR1 (0.70) | SIGMAR1ADRB2ADRB1HTR1AADORA3 | |
| SCHEMBL27968317 | 0.85 | SIGMAR1 (0.53) | SIGMAR1SLC6A4 | |
| SCHEMBL3464964 | 0.84 | SIGMAR1 (0.77) | SIGMAR1ADRB2ADRB1HTR1AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0359063-B1 | Antibody having high affinity to methamphetamine and immunogen for obtaining the same | MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) | 1994-03-02 | — | — | EP | claimed |
| US-5233025-A | Amphetamine protein complex as immunogen for obtaining antibodies specific to methamphetamine | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1993-08-03 | — | — | US | claimed |
| US-5026827-A | Amphetamine-protein complex as immunogen for obtaining antibodies specific to methamphetamine | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1991-06-25 | — | — | US | claimed |
| EP-0359063-A2 | Antibody having high affinity to methamphetamine and immunogen for obtaining the same | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1990-03-21 | — | — | EP | claimed |
| CN-1977166-B | Detection of methamphetamine class of drugs | COZART BIOSCIENCE LTD | 2013-01-30 | — | — | CN | disclosed |
| US-7888040-B2 | highly specific; methamphetamine, ecstacy, (+/-)-N-methyl-1-(3,4-methylenedioxyphenyl)-2-butanamine (MBDB) and (+/-)-3,4-methylenedioxyethylamphetamine (MDEA); for use in the laboratory, point-of-care and on-site testing; without significant interference from other phenyethylamine derivatives | CONCATENO UK LIMITED (GB) | 2011-02-15 | — | — | US | disclosed |
| US-20080286816-A1 | Detection of Methamphetamine Group Drugs | COZART BIOSCIENCE LIMITED (GB) | 2008-11-20 | — | — | US | disclosed |
| EP-1756575-B1 | DETECTION OF METHAMPHETAMINE GROUP DRUGS | COZART BIOSCIENCE LTD (GB) | 2008-10-22 | — | — | EP | disclosed |
| EP-1756575-A2 | DETECTION OF METHAMPHETAMINE GROUP DRUGS | Cozart Bioscience Limited (GB) | 2007-02-28 | — | — | EP | disclosed |
| WO-2005121793-A2 | DETECTION OF METHAMPHETAMINE GROUP DRUGS | COZART BIOSCIENCE LIMITED (GB) | 2005-12-22 | — | — | WO | disclosed |
| CN-1187618-C | Reagent box for fast detecting methyl amphetamine and its preparation process | KAICHUANG BIOTECHNOLOGY CO LTD (CN) | 2005-02-02 | — | — | CN | disclosed |
| CN-1124341-C | Monoclonal antibody specific for methamphetamine, hybridoma producing the same, kit containing the same and use thereof | BIOTECHNOLOGY DEV CT (CN) | 2003-10-15 | — | — | CN | disclosed |
| US-5243074-A | IMMUNOREAGENTS | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1993-09-07 | — | — | US | disclosed |
| US-5233025-A | Amphetamine protein complex as immunogen for obtaining antibodies specific to methamphetamine | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1993-08-03 | — | — | US | disclosed |
| US-5233025-A | Amphetamine protein complex as immunogen for obtaining antibodies specific to methamphetamine | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1993-08-03 | — | — | US | disclosed |
| US-5229302-A | Fluorescence immunoassay method utilizing pseudo-antigens combined with fluorescent quenchers | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1993-07-20 | — | — | US | disclosed |
| US-5026827-A | Amphetamine-protein complex as immunogen for obtaining antibodies specific to methamphetamine | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1991-06-25 | — | — | US | disclosed |
| EP-0430020-A1 | Immunoassay and immunoreagents | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1991-06-05 | — | — | EP | disclosed |
| EP-0359063-A2 | Antibody having high affinity to methamphetamine and immunogen for obtaining the same | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1990-03-21 | — | — | EP | disclosed |
| EP-0343346-A1 | Fluorescence immunoassay method utilizing pseudo-antigens combined with fluorescent quenchers | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1989-11-29 | — | — | EP | disclosed |