Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 19/20 | 0.73 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.58 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.58 |
| ▸ | DRD2 | P14416 | 1/20 | 0.58 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.58 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.58 |
| ▸ | CNR1 | P21554 | 1/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.58 |
| ▸ | HTR2A | P28223 | 1/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.58 |
| ▸ | MC4R | P32245 | 1/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.58 |
| ▸ | HRH1 | P35367 | 1/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.58 |
| ▸ | DRD3 | P35462 | 1/20 | 0.58 |
| ▸ | SCN1A | P35498 | 1/20 | 0.58 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1202012 | 1.00 | SIGMAR1 (0.73) | SIGMAR1ADRB2ADRB1HTR1AADORA3 | |
| SCHEMBL9175505 | 1.00 | SIGMAR1 (0.73) | SIGMAR1ADRB2ADRB1HTR1AADORA3 | |
| SCHEMBL9191015 | 0.95 | SIGMAR1 (0.72) | SIGMAR1ADRB2ADRB1HTR1AADORA3 | |
| SCHEMBL30384619 | 0.91 | SIGMAR1 (0.86) | SIGMAR1ADRB2ADRB1HTR1AADORA3 | |
| SCHEMBL20689723 | 0.89 | SIGMAR1 (0.86) | SIGMAR1ADRB2ADRB1HTR1AADORA3 | |
| SCHEMBL20689707 | 0.89 | SIGMAR1 (0.86) | SIGMAR1ADRB2ADRB1HTR1AADORA3 | |
| SCHEMBL20689714 | 0.89 | SIGMAR1 (0.86) | SIGMAR1ADRB2ADRB1HTR1AADORA3 | |
| SCHEMBL5577576 | 0.87 | SIGMAR1 (0.70) | SIGMAR1ADRB2ADRB1HTR1AADORA3 | |
| SCHEMBL27968317 | 0.85 | SIGMAR1 (0.53) | SIGMAR1SLC6A4 | |
| SCHEMBL3464964 | 0.84 | SIGMAR1 (0.77) | SIGMAR1ADRB2ADRB1HTR1AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2142928-B1 | ASSAY DEVICES AND COMPONENTS FOR USE THEREIN | SELECTIVE ANTIBODIES LTD (GB) | 2018-11-07 | — | — | EP | disclosed |
| US-8389296-B2 | Assay devices and methods and components for use therein | SELECTIVE ANTIBODIES LIMITED (GB) | 2013-03-05 | — | — | US | disclosed |
| US-20100209295-A1 | ASSAY DEVICES AND METHODS AND COMPONENTS FOR USE THEREIN | SELECTIVE ANTIBODIES LIMITED (GB) | 2010-08-19 | — | — | US | disclosed |
| EP-2142928-A1 | ASSAY DEVICES AND METHODS AND COMPONENTS FOR USE THEREIN | Selective Antibodies Limited (GB) | 2010-01-13 | — | — | EP | disclosed |
| WO-2008129302-A1 | ASSAV DEVICES AND METHODS AND COMPONENTS FOR USE THEREIN | SELECTIVE ANTIBODIES LIMITED (GB) | 2008-10-30 | — | — | WO | disclosed |