Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 15/20 | 0.70 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.64 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.64 |
| ▸ | HTR1A | P08908 | 1/20 | 0.64 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.64 |
| ▸ | DRD2 | P14416 | 1/20 | 0.64 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.64 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.64 |
| ▸ | CNR1 | P21554 | 1/20 | 0.64 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.64 |
| ▸ | HTR2A | P28223 | 1/20 | 0.64 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.64 |
| ▸ | MC4R | P32245 | 1/20 | 0.64 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.64 |
| ▸ | HRH1 | P35367 | 1/20 | 0.64 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.64 |
| ▸ | DRD3 | P35462 | 1/20 | 0.64 |
| ▸ | SCN1A | P35498 | 1/20 | 0.64 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.64 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9191015 | 0.89 | SIGMAR1 (0.72) | SIGMAR1ADRB2ADRB1HTR1AADORA3 | |
| SCHEMBL29059547 | 0.88 | SIGMAR1 (0.81) | SIGMAR1ADRB2ADRB1HTR1AADORA3 | |
| SCHEMBL1202012 | 0.87 | SIGMAR1 (0.73) | SIGMAR1ADRB2ADRB1HTR1AADORA3 | |
| SCHEMBL9175505 | 0.87 | SIGMAR1 (0.73) | SIGMAR1ADRB2ADRB1HTR1AADORA3 | |
| SCHEMBL2778709 | 0.87 | SIGMAR1 (0.73) | SIGMAR1ADRB2ADRB1HTR1AADORA3 | |
| SCHEMBL13181363 | 0.85 | SIGMAR1 (0.70) | SIGMAR1ADRB2ADRB1HTR1AADORA3 | |
| SCHEMBL15887532 | 0.85 | SIGMAR1 (0.70) | SIGMAR1ADRB2ADRB1HTR1AADORA3 | |
| SCHEMBL30384619 | 0.84 | SIGMAR1 (0.86) | SIGMAR1ADRB2ADRB1HTR1AADORA3 | |
| SCHEMBL9115931 | 0.84 | SIGMAR1 (0.68) | SIGMAR1ADRB2ADRB1HTR1AADORA3 | |
| SCHEMBL11410303 | 0.83 | SIGMAR1 (0.49) | SIGMAR1ADRB2ADRB1HTR1AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7169907-B2 | Derivatives, immunogens, and antibodies for detecting ecstasy-class drugs | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2007-01-30 | — | — | US | disclosed |
| EP-0399184-B1 | Reagents, methods and kits for an amphetamine-class fluorescence polarization immunoassay | ABBOTT LAB (US) | 1995-09-13 | — | — | EP | disclosed |
| US-5354693-A | Reagents, methods and kits for an amphetamine-class fluorescence polarization immunoassy | ABBOTT LABORATORIES (US) | 1994-10-11 | — | — | US | disclosed |
| US-5248791-A | Reagents, methods and kits for an amphetamine-class fluorescence polarization immunoassay | ABBOTT LABORATORIES (US) | 1993-09-28 | — | — | US | disclosed |
| EP-0399184-A2 | Reagents, methods and kits for an amphetamine-class fluorescence polarization immunoassay | ABBOTT LABORATORIES (US) | 1990-11-28 | — | — | EP | disclosed |