Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 6/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MMP1 | P03956 | 5/20 | 0.38 |
| ▸ | MMP9 | P14780 | 5/20 | 0.38 |
| ▸ | MMP13 | P45452 | 5/20 | 0.38 |
| ▸ | MMP3 | P08254 | 4/20 | 0.38 |
| ▸ | MMP7 | P09237 | 4/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11763255 | 0.84 | G6PD (0.44) | CA12CA2KMT2AMEN1ALDH1A1 | |
| SCHEMBL14537429 | 0.82 | MMP2 (0.44) | MMP2CA12CA14PLCG1CA2 | |
| SCHEMBL12463013 | 0.80 | MMP2 (0.47) | MMP2CA12CA14PLCG1CA2 | |
| SCHEMBL13813079 | 0.78 | MMP2 (0.47) | MMP2CA12CA14PLCG1CA2 | |
| SCHEMBL12674211 | 0.78 | MMP2 (0.47) | MMP2CA12CA14PLCG1CA2 | |
| SCHEMBL13917416 | 0.77 | PLCG1 (0.52) | PLCG1CA2KMT2AMMP1MMP13 | |
| SCHEMBL3059582 | 0.77 | MMP2 (0.43) | MMP2CA12CA14PLCG1CA2 | |
| SCHEMBL152957 | 0.73 | MMP2 (0.53) | MMP2CA12CA14PLCG1CA2 | |
| SCHEMBL10258225 | 0.73 | PLCG1 (0.55) | PLCG1CA2KMT2AMMP1MMP13 | |
| SCHEMBL27183394 | 0.72 | MMP2 (0.50) | MMP2CA12CA14PLCG1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120220530-A1 | ALBUMIN VARIANTS | NOVOZYMES BIOPHARMA DK A/S (DK) | 2012-08-30 | — | — | US | disclosed |