Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | GAA | P10253 | 6/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CFTR | P13569 | 6/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3618785 | 0.84 | GAA (0.52) | KDM4EALDH1A1GAAHSD17B10HPGD | |
| SCHEMBL24413980 | 0.81 | KDM4E (0.47) | KDM4EALDH1A1GAAHSD17B10HPGD | |
| SCHEMBL681252 | 0.81 | KDM4E (0.63) | KDM4EALDH1A1GAAHSD17B10HPGD | |
| SCHEMBL2387487 | 0.80 | KDM4E (0.47) | KDM4EALDH1A1GAAHSD17B10HPGD | |
| SCHEMBL23015341 | 0.79 | KDM4E (0.50) | KDM4EALDH1A1GAAHSD17B10HPGD | |
| SCHEMBL2391637 | 0.79 | CFTR (0.63) | KDM4EALDH1A1GAAHSD17B10HPGD | |
| SCHEMBL13259196 | 0.79 | GAA (0.44) | KDM4EALDH1A1GAAHSD17B10HPGD | |
| SCHEMBL4758833 | 0.76 | KDM4E (0.73) | KDM4EALDH1A1GAAHSD17B10HPGD | |
| SCHEMBL25369023 | 0.76 | KDM4E (0.58) | KDM4EALDH1A1GAAHSD17B10HPGD | |
| SCHEMBL2897750 | 0.75 | KDM4E (0.61) | KDM4EALDH1A1GAAHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130296332-A1 | 1H-QUINAZOLINE-2,4-DIONES | NOVARTIS AG (CH) | 2013-11-07 | — | — | US | disclosed |
| US-8513268-B2 | 1H-quinazoline-2,4-diones processes for their production, pharmaceutical compositions, and treatment for epilepsy | NOVARTIS AG (CH) | 2013-08-20 | — | — | US | disclosed |
| US-20110294818-A1 | 1H-QUINAZOLINE-2,4-DIONES | NOVARTIS AG | 2011-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110294818-A1 | 1H-QUINAZOLINE-2,4-DIONES | CYP1A2, QDPR, CYP3A7 | KDM4E 1242/4885ALDH1A1 115/4885GAA 1401/4885 |
| US-20130296332-A1 | 1H-QUINAZOLINE-2,4-DIONES | CYP1A2, QDPR, CYP3A7 | KDM4E 1242/4885ALDH1A1 115/4885GAA 1401/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.