Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13376552 | 0.86 | NR3C1 (0.68) | NR3C1GLUL | |
| SCHEMBL13376688 | 0.86 | NR3C1 (0.68) | NR3C1GLUL | |
| SCHEMBL14115979 | 0.86 | NR3C1 (0.68) | NR3C1GLUL | |
| SCHEMBL12956206 | 0.86 | NR3C1 (0.67) | NR3C1GLUL | |
| SCHEMBL14091722 | 0.85 | NR3C1 (0.67) | NR3C1GLUL | |
| SCHEMBL14091724 | 0.85 | NR3C1 (0.67) | NR3C1GLUL | |
| SCHEMBL12671990 | 0.85 | NR3C1 (0.66) | NR3C1GLUL | |
| SCHEMBL12638273 | 0.85 | NR3C1 (0.66) | NR3C1GLUL | |
| SCHEMBL12947476 | 0.85 | NR3C1 (0.66) | NR3C1GLUL | |
| SCHEMBL11961039 | 0.85 | NR3C1 (0.89) | NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2091922-B1 | 2-[1-PHENYL-5-HYDROXY-4ALPHA-METHYL-HEXAHYDROCYCLOPENTA[F]INDAZOL-5-YL]ETHYL PHENYL DERIVATIVES AS GLUCOCORTICOID RECEPTOR LIGANDS | MERCK SHARP & DOHME (US) | 2011-12-21 | — | — | EP | disclosed |
| WO-2008060391-A2 | 2- [L-PHENYL-5-HYDR0XY-4ALPHA-METHYL-HEXAHYDR0CYCL0PENTA[F] INDAZ0L-5-YL] ETHYL PHENYL DERIVATIVES AS GLUCOCORTICOID RECEPTOR LIGANDS | MERCK & CO., INC. (US) | 2008-05-22 | — | — | WO | disclosed |
| WO-2008051532-A1 | 2-[1-PHENYL-5-HYDROXY OR METHOXY-4ALPHA-METHYL-HEXAHYDROCLOPENTA[F]INDAZOL-5-YL]ETHYL PHENYL DERIVATIVES AS GLUCOCORTICOID RECEPTOR LIGANDS | MERCK & CO., INC. (US) | 2008-05-02 | — | — | WO | disclosed |