Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2738606 | 0.86 | ALDH1A1 (0.47) | ALDH1A1POLBCHRM2KMT2ALMNA | |
| SCHEMBL2738743 | 0.86 | ALDH1A1 (0.47) | ALDH1A1POLBCHRM2KMT2ALMNA | |
| SCHEMBL2738773 | 0.81 | KCNA3 (0.38) | ALDH1A1HTTHTR2AOPRD1MITF | |
| SCHEMBL8223521 | 0.73 | MEN1 (0.53) | ALDH1A1POLBHTTCHRM2CHRM1 | |
| SCHEMBL2739199 | 0.73 | MEN1 (0.53) | ALDH1A1POLBHTTCHRM2CHRM1 | |
| SCHEMBL684992 | 0.72 | ALDH1A1 (0.48) | ALDH1A1POLBCHRM2KMT2ALMNA | |
| SCHEMBL684688 | 0.72 | ALDH1A1 (0.48) | ALDH1A1POLBCHRM2KMT2ALMNA | |
| SCHEMBL30499325 | 0.72 | ALDH1A1 (0.44) | ALDH1A1HTTLMNA | |
| SCHEMBL8223281 | 0.71 | NTSR1 (0.56) | ALDH1A1POLBHTTMITFRAB9A | |
| SCHEMBL2738589 | 0.71 | NTSR1 (0.56) | ALDH1A1POLBHTTMITFRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2399909-A1 | Hydroxylated and methoxylated cyclopenta[d]pyrimidines as akt protein kinase inhibitors | Array Biopharma, Inc. (US) | 2011-12-28 | — | — | EP | disclosed |