Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12032254 | 0.90 | GRIN2D (0.41) | THRBALDH1A1MAPTMAPK1LMNA | |
| SCHEMBL26362335 | 0.80 | ELANE (0.40) | THRBALDH1A1MAPTMAPK1GRIN2D | |
| SCHEMBL1724042 | 0.78 | THRB (0.49) | THRBALDH1A1MAPTMAPK1CYP3A4 | |
| SCHEMBL18051656 | 0.77 | THRB (0.47) | THRBALDH1A1MAPTMAPK1CYP3A4 | |
| SCHEMBL26362324 | 0.76 | THRB (0.42) | THRBMAPTGRIN2DGRIN3BGRIN1 | |
| Biphenyl SCHEMBL17893027 | 0.76 | THRB (0.53) | THRBALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL28771131 | 0.75 | THRB (0.45) | THRBALDH1A1MAPTMAPK1LMNA | |
| SCHEMBL19846629 | 0.74 | THRB (0.51) | THRBALDH1A1MAPK1CYP3A4TP53 | |
| Biphenyl SCHEMBL29229525 | 0.74 | THRB (0.54) | THRBALDH1A1MAPTMAPK1LMNA | |
| Biphenyl SCHEMBL5899505 | 0.73 | MAPT (0.45) | THRBALDH1A1MAPTMAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8335148-B2 | Polymerizable compound, polymerizable composition, optical material, optical element and optical head device | ASAHI GLASS COMPANY, LIMITED (JP) | 2012-12-18 | — | — | US | disclosed |
| US-8335148-B2 | Polymerizable compound, polymerizable composition, optical material, optical element and optical head device | ASAHI GLASS COMPANY, LIMITED (JP) | 2012-12-18 | — | — | US | disclosed |
| US-20110310721-A1 | POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, OPTICAL MATERIAL, OPTICAL ELEMENT AND OPTICAL HEAD DEVICE | ASAHI GLASS COMPANY, LIMITED (JP) | 2011-12-22 | — | — | US | disclosed |
| US-20110310721-A1 | POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, OPTICAL MATERIAL, OPTICAL ELEMENT AND OPTICAL HEAD DEVICE | ASAHI GLASS COMPANY, LIMITED (JP) | 2011-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110310721-A1 | POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, OPTICAL MATERIAL, OPTICAL ELEMENT AND OPTICAL HEAD DEVICE | H1-0, H1-2, SUV39H2 | THRB 552/4885ALDH1A1 4073/4885MAPT 3949/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.