Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 2/20 | 0.40 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.39 |
| ▸ | TEK | Q02763 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12032239 | 0.90 | THRB (0.44) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL26362335 | 0.82 | ELANE (0.40) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL12032213 | 0.79 | RXRA (0.43) | ALDH1A1HIF1ATP53CYP3A4LMNA | |
| SCHEMBL26362324 | 0.77 | THRB (0.42) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL10002221 | 0.76 | SMN1; SMN2 (0.50) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL26116339 | 0.76 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2CYP3A4APEX1TDP1 | |
| SCHEMBL26118948 | 0.76 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2CYP3A4APEX1TDP1 | |
| SCHEMBL12039352 | 0.73 | THRB (0.65) | ALDH1A1SMN1; SMN2HIF1ATP53LMNA | |
| SCHEMBL8816210 | 0.72 | CYP3A4 (0.46) | ALDH1A1SMN1; SMN2MAPK1HIF1ATP53 | |
| SCHEMBL34007 | 0.72 | MAPT (0.54) | ALDH1A1SMN1; SMN2MAPK1LMNAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8335148-B2 | Polymerizable compound, polymerizable composition, optical material, optical element and optical head device | ASAHI GLASS COMPANY, LIMITED (JP) | 2012-12-18 | — | — | US | disclosed |
| US-8335148-B2 | Polymerizable compound, polymerizable composition, optical material, optical element and optical head device | ASAHI GLASS COMPANY, LIMITED (JP) | 2012-12-18 | — | — | US | disclosed |
| US-20110310721-A1 | POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, OPTICAL MATERIAL, OPTICAL ELEMENT AND OPTICAL HEAD DEVICE | ASAHI GLASS COMPANY, LIMITED (JP) | 2011-12-22 | — | — | US | disclosed |
| US-20110310721-A1 | POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, OPTICAL MATERIAL, OPTICAL ELEMENT AND OPTICAL HEAD DEVICE | ASAHI GLASS COMPANY, LIMITED (JP) | 2011-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110310721-A1 | POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, OPTICAL MATERIAL, OPTICAL ELEMENT AND OPTICAL HEAD DEVICE | H1-0, H1-2, SUV39H2 | GRIN2D 1742/4885GRIN3B 3552/4885GRIN1 2371/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.